Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
Key Points. RNA-seq analysis of CD34+ cells identifies novel aberrantly spliced genes and dysregulated pathways in splicing factor mutant MDS.Aberrantly splice
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 September 2018
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| In: |
Blood
Year: 2018, Jahrgang: 132, Heft: 12, Pages: 1225-1240 |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood-2018-04-843771 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1182/blood-2018-04-843771
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| Verfasserangaben: | Andrea Pellagatti, Richard N. Armstrong, Violetta Steeples, Eshita Sharma, Emmanouela Repapi, Shalini Singh, Andrea Sanchi, Aleksandar Radujkovic, Patrick Horn, Hamid Dolatshad, Swagata Roy, John Broxholme, Helen Lockstone, Stephen Taylor, Aristoteles Giagounidis, Paresh Vyas, Anna Schuh, Angela Hamblin, Elli Papaemmanuil, Sally Killick, Luca Malcovati, Marco L. Hennrich, Anne-Claude Gavin, Anthony D. Ho, Thomas Luft, Eva Hellström-Lindberg, Mario Cazzola, Christopher W. J. Smith, Stephen Smith, and Jacqueline Boultwood |
| Zusammenfassung: | Key Points. RNA-seq analysis of CD34+ cells identifies novel aberrantly spliced genes and dysregulated pathways in splicing factor mutant MDS.Aberrantly splice |
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| Beschreibung: | Gesehen am 07.02.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood-2018-04-843771 |