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Multicentric analytical comparability study of programmed death-ligand 1 expression on tumor-infiltrating immune cells and tumor cells in urothelial bladder cancer using four clinically developed immunohistochemistry assays

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Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) correlated in several studies with PD-L1/programmed death-1 (PD-1) checkpoint inhibitor efficacy. Since June 2018, a positive PD-L1 status is required for atezolizumab or pembrolizumab treatment...

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Main Authors: Schwamborn, Kristina (Author) , Lasitschka, Felix (Author) , Schirmacher, Peter (Author)
Format: Article (Journal)
Language:English
Published: 2 July 2019
In: Virchows Archiv
Year: 2019, Volume: 475, Issue: 5, Pages: 599-608
ISSN:1432-2307
DOI:10.1007/s00428-019-02610-z
Online Access:Verlag, Volltext: https://doi.org/10.1007/s00428-019-02610-z
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Author Notes:Kristina Schwamborn, Johannes U. Ammann, Ruth Knüchel, Arndt Hartmann, Gustavo Baretton, Felix Lasitschka, Peter Schirmacher, Till Braunschweig, Robert Tauber, Franziska Erlmeier, Stefanie Hieke-Schulz, Wilko Weichert
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Programmed Death Ligand-1 (PD-L1) is an independent negative prognosticator in Western-world gallbladder cancer by Albrecht, Thomas (Author) , Brinkmann, Fritz (Author) , Albrecht, Michael (Author) , Lonsdorf, Anke Susanne (Author) , Mehrabi, Arianeb (Author) , Hoffmann, Katrin (Author) , Kulu, Yakup (Author) , Charbel, Alphonse (Author) , Vogel, Monika Nadja (Author) , Rupp, Christian (Author) , Köhler, Bruno Christian (Author) , Springfeld, Christoph (Author) , Schirmacher, Peter (Author) , Rössler, Stephanie (Author) , Goeppert, Benjamin (Author) ,


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RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury by Subramanian, Santosh Krishna (Author) , Schirmacher, Peter (Author) ,


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Response to anti-programmed cell death protein-1 antibodies in men treated for platinum refractory germ cell cancer relapsed after high-dose chemotherapy and stem cell transplantat... by Zschäbitz, Stefanie (Author) , Lasitschka, Felix (Author) , Hadaschik, Boris (Author) , Hofheinz, Ralf-Dieter (Author) , Jäger, Dirk (Author) , Grüllich, Carsten (Author) ,


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