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Multicentric analytical comparability study of programmed death-ligand 1 expression on tumor-infiltrating immune cells and tumor cells in urothelial bladder cancer using four clinically developed immunohistochemistry assays

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Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) correlated in several studies with PD-L1/programmed death-1 (PD-1) checkpoint inhibitor efficacy. Since June 2018, a positive PD-L1 status is required for atezolizumab or pembrolizumab treatment...

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Autori principali: Schwamborn, Kristina (Autore) , Lasitschka, Felix (Autore) , Schirmacher, Peter (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: 2 July 2019
In: Virchows Archiv
Year: 2019, Volume: 475, Fascicolo: 5, Pages: 599-608
ISSN:1432-2307
DOI:10.1007/s00428-019-02610-z
Accesso online:Verlag, Volltext: https://doi.org/10.1007/s00428-019-02610-z
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Note sull'autore:Kristina Schwamborn, Johannes U. Ammann, Ruth Knüchel, Arndt Hartmann, Gustavo Baretton, Felix Lasitschka, Peter Schirmacher, Till Braunschweig, Robert Tauber, Franziska Erlmeier, Stefanie Hieke-Schulz, Wilko Weichert
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Response to anti-programmed cell death protein-1 antibodies in men treated for platinum refractory germ cell cancer relapsed after high-dose chemotherapy and stem cell transplantat... di Zschäbitz, Stefanie (Autore) , Lasitschka, Felix (Autore) , Hadaschik, Boris (Autore) , Hofheinz, Ralf-Dieter (Autore) , Jäger, Dirk (Autore) , Grüllich, Carsten (Autore) ,


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