Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI

Ηepatic involvement in multiple myeloma is not common; nevertheless, it is associated with poorer outcome. Heterogeneous features have been described in few published reports so far. We present the imaging findings of PET/CT in comparison to those of MRI for two multiple myeloma (MM) patients, one w...

Full description

Saved in:
Bibliographic Details
Main Authors: Papamichail, Dimitris (Author) , Goldschmidt, Hartmut (Author) , Dimitrakopoulou-Strauss, Antonia (Author)
Format: Article (Journal)
Language:English
Published: 7 November 2019
In: Diagnostics
Year: 2019, Volume: 9, Issue: 4
ISSN:2075-4418
DOI:10.3390/diagnostics9040179
Online Access:Verlag, Volltext: https://doi.org/10.3390/diagnostics9040179
Verlag: https://www.mdpi.com/2075-4418/9/4/179
Get full text
Author Notes:Dimitris Papamichail, Robert Hog, Hartmut Goldschmidt and Antonia Dimitrakopoulou-Strauss

MARC

LEADER 00000caa a2200000 c 4500
001 1690127341
003 DE-627
005 20230427083201.0
007 cr uuu---uuuuu
008 200217s2019 xx |||||o 00| ||eng c
024 7 |a 10.3390/diagnostics9040179  |2 doi 
035 |a (DE-627)1690127341 
035 |a (DE-599)KXP1690127341 
035 |a (OCoLC)1341305455 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Papamichail, Dimitris  |e VerfasserIn  |0 (DE-588)1204846146  |0 (DE-627)1690127988  |4 aut 
245 1 0 |a Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI  |c Dimitris Papamichail, Robert Hog, Hartmut Goldschmidt and Antonia Dimitrakopoulou-Strauss 
264 1 |c 7 November 2019 
300 |a 4 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 17.02.2020 
520 |a Ηepatic involvement in multiple myeloma is not common; nevertheless, it is associated with poorer outcome. Heterogeneous features have been described in few published reports so far. We present the imaging findings of PET/CT in comparison to those of MRI for two multiple myeloma (MM) patients, one with a liver lesion suspicious for myeloma metastasis on PET and one with multiple liver lesions suspicious for myeloma metastases on MRΙ. The subsequent ultrasound-guided needle biopsies confirmed the extramedullary spread of the disease in both patients. The first case exhibited a match in both functional imaging modalities (PET and MRI) but a mismatch of intense metabolic activity on 18F-fluorodeoxyglucose (18F-FDG) PET/CT and iso-attenuating liver parenchyma on contrast-enhanced CT. The second case showed a mismatch of signal elevation persistence on diffusion-weighted imaging (DWI) and physiologic 18F-FDG distribution in the liver parenchyma. These cases present different imaging features in MM lesions of the liver using PET/CT and MRI, reflecting the high disease heterogeneity in patients with MM and demonstrating that the use of both PET/CT and MRI may offer complementary information. 
650 4 |a 18F-FDG PET/CT 
650 4 |a contrast-enhanced CT 
650 4 |a extramedullary 
650 4 |a MRI 
650 4 |a multiple myeloma 
700 1 |a Goldschmidt, Hartmut  |d 1956-  |e VerfasserIn  |0 (DE-588)102258023X  |0 (DE-627)717003809  |0 (DE-576)365637386  |4 aut 
700 1 |a Dimitrakopoulou-Strauss, Antonia  |d 1963-  |e VerfasserIn  |0 (DE-588)1076688373  |0 (DE-627)835256901  |0 (DE-576)167486055  |4 aut 
773 0 8 |i Enthalten in  |t Diagnostics  |d Basel : MDPI, 2011  |g 9(2019,4) Artikel-Nummer 179, 4 Seiten  |h Online-Ressource  |w (DE-627)718627814  |w (DE-600)2662336-5  |w (DE-576)365413917  |x 2075-4418  |7 nnas  |a Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI 
773 1 8 |g volume:9  |g year:2019  |g number:4  |g extent:4  |a Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI 
856 4 0 |u https://doi.org/10.3390/diagnostics9040179  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://www.mdpi.com/2075-4418/9/4/179  |x Verlag 
951 |a AR 
992 |a 20200217 
993 |a Article 
994 |a 2019 
998 |g 1076688373  |a Dimitrakopoulou-Strauss, Antonia  |m 1076688373:Dimitrakopoulou-Strauss, Antonia  |d 50000  |e 50000PD1076688373  |k 0/50000/  |p 4  |y j 
998 |g 102258023X  |a Goldschmidt, Hartmut  |m 102258023X:Goldschmidt, Hartmut  |d 910000  |d 910100  |e 910000PG102258023X  |e 910100PG102258023X  |k 0/910000/  |k 1/910000/910100/  |p 3 
999 |a KXP-PPN1690127341  |e 3595959256 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Dimitris Papamichail, Robert Hog, Hartmut Goldschmidt and Antonia Dimitrakopoulou-Strauss"]},"person":[{"role":"aut","display":"Papamichail, Dimitris","given":"Dimitris","family":"Papamichail","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","family":"Goldschmidt","role":"aut","display":"Goldschmidt, Hartmut","given":"Hartmut"},{"role":"aut","display":"Dimitrakopoulou-Strauss, Antonia","given":"Antonia","roleDisplay":"VerfasserIn","family":"Dimitrakopoulou-Strauss"}],"physDesc":[{"extent":"4 S."}],"relHost":[{"title":[{"subtitle":"open access journal","title":"Diagnostics","title_sort":"Diagnostics"}],"id":{"issn":["2075-4418"],"zdb":["2662336-5"],"eki":["718627814"]},"disp":"Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRIDiagnostics","note":["Gesehen am 28.05.2020"],"physDesc":[{"extent":"Online-Ressource"}],"part":{"extent":"4","year":"2019","issue":"4","volume":"9","text":"9(2019,4) Artikel-Nummer 179, 4 Seiten"},"origin":[{"dateIssuedDisp":"2011-","publisherPlace":"Basel","dateIssuedKey":"2011","publisher":"MDPI"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"pubHistory":["1.2011 -"],"recId":"718627814"}],"language":["eng"],"origin":[{"dateIssuedKey":"2019","dateIssuedDisp":"7 November 2019"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI","title_sort":"Imaging features of multiple myeloma extramedullary lesions in the liver with 18F-FDG PET/CT, contrast-enhanced CT and MRI"}],"id":{"eki":["1690127341"],"doi":["10.3390/diagnostics9040179"]},"recId":"1690127341","note":["Gesehen am 17.02.2020"]} 
SRT |a PAPAMICHAIIMAGINGFEA7201