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Mechano-redox control of integrin de-adhesion

How proteins harness mechanical force to control function is a significant biological question. Here we describe a human cell surface receptor that couples ligand binding and force to trigger a chemical event which controls the adhesive properties of the receptor. Our studies of the secreted platele...

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Bibliographic Details
Main Authors: Passam, Freda (Author) , Kolšek, Katra (Author) , Thärichen, Lena (Author) , Aponte-Santamaria, Camilo (Author) , Gräter, Frauke (Author)
Format: Article (Journal)
Language:English
Published: 22 June 2018
In: eLife
Year: 2018, Volume: 7
ISSN:2050-084X
DOI:10.7554/eLife.34843
Online Access:Verlag, Volltext: https://doi.org/10.7554/eLife.34843
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Author Notes:Freda Passam, Joyce Chiu, Lining Ju, Aster Pijning, Zeenat Jahan, Ronit Mor-Cohen, Adva Yeheskel, Katra Kolšek, Lena Thärichen, Camilo Aponte-Santamaría, Frauke Gräter, Philip J Hogg

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