Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer
The evolution and genetic nature of metastatic lesions is not completely characterized. Here the authors perform a comprehensive whole-genome study of colorectal metastases in comparison to matched primary tumors and define a multistage progression model and metastasis-specific changes that, in part...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
14 November 2018
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| In: |
Nature Communications
Year: 2018, Jahrgang: 9 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-07041-z |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41467-018-07041-z Verlag, Volltext: https://www.nature.com/articles/s41467-018-07041-z 
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| Verfasserangaben: | Naveed Ishaque, Mohammed L. Abba, Christine Hauser, Nitin Patil, Nagarajan Paramasivam, Daniel Huebschmann, Jörg Hendrik Leupold, Gnana Prakash Balasubramanian, Kortine Kleinheinz, Umut H. Toprak, Barbara Hutter, Axel Benner, Anna Shavinskaya, Chan Zhou, Zuguang Gu, Jules Kerssemakers, Alexander Marx, Marcin Moniuszko, Miroslaw Kozlowski, Joanna Reszec, Jacek Niklinski, Jürgen Eils, Matthias Schlesner, Roland Eils, Benedikt Brors, Heike Allgayer |
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