Neurovascular communication during CNS development

A precise communication between the nervous and the vascular systems is crucial for proper formation and function of the central nervous system (CNS). Interestingly, this communication does not only occur by neural cells regulating the growth and properties of the vasculature, but new studies show t...

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Hauptverfasser: Paredes Ugarte, Isidora B. (VerfasserIn) , Himmels, Patricia (VerfasserIn) , Ruiz de Almodóvar, Carmen (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 9 April 2018
In: Developmental cell
Year: 2018, Jahrgang: 45, Heft: 1, Pages: 10-32
ISSN:1878-1551
DOI:10.1016/j.devcel.2018.01.023
Online-Zugang:Verlag, Volltext: https://doi.org/10.1016/j.devcel.2018.01.023
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1534580718300583
Volltext
Verfasserangaben:Isidora Paredes, Patricia Himmels, and Carmen Ruiz de Almodóvar
Beschreibung
Zusammenfassung:A precise communication between the nervous and the vascular systems is crucial for proper formation and function of the central nervous system (CNS). Interestingly, this communication does not only occur by neural cells regulating the growth and properties of the vasculature, but new studies show that blood vessels actively control different neurodevelopmental processes. Here, we review the current knowledge on how neurons in particular influence growing blood vessels during CNS development and on how vessels participate in shaping the neural compartment. We also review the identified molecular mechanisms of this bidirectional communication.
Beschreibung:Gesehen am 21.02.2020
Beschreibung:Online Resource
ISSN:1878-1551
DOI:10.1016/j.devcel.2018.01.023