Radiologic progression of glioblastoma under therapy: an exploratory analysis of AVAglio

Abstract: Background. In this exploratory analysis of AVAglio, a randomized phase III clinical study that investigated the addition of bevacizumab (Bev) to radiotherapy/temozolomide in newly diagnosed glioblastoma, we aim to radiologically characterize glioblastoma on therapy until progression and i...

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Main Authors: Nowosielski, Martha (Author) , Ellingson, Benjamin M. (Author) , Chinot, Olivier L. (Author) , Garcia, Josep (Author) , Revil, Cedric (Author) , Radbruch, Alexander (Author) , Nishikawa, Ryo (Author) , Mason, Warren P. (Author) , Henriksson, Roger (Author) , Saran, Frank (Author) , Vollmuth, Philipp (Author) , Platten, Michael (Author) , Sandmann, Thomas (Author) , Abrey, Lauren E. (Author) , Cloughesy, Timothy F. (Author) , Bendszus, Martin (Author) , Wick, Wolfgang (Author)
Format: Article (Journal)
Language:English
Published: 2018
In: Neuro-Oncology
Year: 2017, Volume: 20, Issue: 4, Pages: 557-566
ISSN:1523-5866
DOI:10.1093/neuonc/nox162
Online Access:Verlag, Volltext: https://doi.org/10.1093/neuonc/nox162
Verlag, Volltext: https://academic.oup.com/neuro-oncology/article/20/4/557/4102288
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Author Notes:Martha Nowosielski, Benjamin M. Ellingson, Olivier L. Chinot, Josep Garcia, Cedric Revil, Alexander Radbruch, Ryo Nishikawa, Warren P. Mason, Roger Henriksson, Frank Saran, Philipp Kickingereder, Michael Platten, Thomas Sandmann, Lauren E. Abrey, Timothy F. Cloughesy, Martin Bendszus, and Wolfgang Wick
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Summary:Abstract: Background. In this exploratory analysis of AVAglio, a randomized phase III clinical study that investigated the addition of bevacizumab (Bev) to radiotherapy/temozolomide in newly diagnosed glioblastoma, we aim to radiologically characterize glioblastoma on therapy until progression and investigate whether the type of radiologic progression differs between treatment arms and is related to survival and molecular data
Item Description:Published: 01 September 2017
Gesehen am 26.02.2020
Physical Description:Online Resource
ISSN:1523-5866
DOI:10.1093/neuonc/nox162