Trial supports targeted radiotherapy for early breast cancer but protocol still requires 3 weeks of daily therapy
Commentary on: Coles CE, Griffin CL, Kirby AM, et al . IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;3...
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| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 January 2018
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| In: |
Evidence based medicine
Year: 2018, Volume: 23, Issue: 1, Pages: 38-39 |
| ISSN: | 1473-6810 |
| DOI: | 10.1136/ebmed-2017-110849 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1136/ebmed-2017-110849 Verlag, Volltext: https://ebm.bmj.com/content/23/1/38 
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| Author Notes: | Jayant S Vaidya, Frederik Wenz, Jeffrey S Tobias |
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| 500 | |a Commentary on: Coles CE, Griffin CL, Kirby AM, et al. IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;390:1048–60 | ||
| 500 | |a Gesehen am 28.02.2020 | ||
| 520 | |a Commentary on: Coles CE, Griffin CL, Kirby AM, et al . IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;390:1048-60. - - The evidence-based local treatment for early breast cancer is breast-conserving surgery and radiotherapy, requiring 3-6 weeks of daily whole breast external beam radiation therapy, which is inconvenient for patients and expensive. - - The suggestion that targeted radiation to the tumour bed with modern techniques may be adequate was proposed in 1995.1 This was heralded as a new standard2 with the publication of the TARGIT-A trial3 4 of single-dose targeted intraoperative radiotherapy (TARGIT-IORT), later confirmed by other European studies using brachytherapy5 that requires 5 days of inpatient stay or EBRT.6 - - In this study,7 in 30 UK centres, from 2007 … | ||
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