Buchumschlag

Trial supports targeted radiotherapy for early breast cancer but protocol still requires 3 weeks of daily therapy

Commentary on: Coles CE, Griffin CL, Kirby AM, et al . IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;3...

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Bibliographische Detailangaben
Hauptverfasser: Vaidya, Jayant S. (VerfasserIn) , Wenz, Frederik (VerfasserIn) , Tobias, Jeffrey S. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 24 January 2018
In: Evidence based medicine
Year: 2018, Jahrgang: 23, Heft: 1, Pages: 38-39
ISSN:1473-6810
DOI:10.1136/ebmed-2017-110849
Online-Zugang:Verlag, Volltext: https://doi.org/10.1136/ebmed-2017-110849
Verlag, Volltext: https://ebm.bmj.com/content/23/1/38
Volltext
Verfasserangaben:Jayant S Vaidya, Frederik Wenz, Jeffrey S Tobias
Beschreibung
Zusammenfassung:Commentary on: Coles CE, Griffin CL, Kirby AM, et al . IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;390:1048-60. - - The evidence-based local treatment for early breast cancer is breast-conserving surgery and radiotherapy, requiring 3-6 weeks of daily whole breast external beam radiation therapy, which is inconvenient for patients and expensive. - - The suggestion that targeted radiation to the tumour bed with modern techniques may be adequate was proposed in 1995.1 This was heralded as a new standard2 with the publication of the TARGIT-A trial3 4 of single-dose targeted intraoperative radiotherapy (TARGIT-IORT), later confirmed by other European studies using brachytherapy5 that requires 5 days of inpatient stay or EBRT.6 - - In this study,7 in 30 UK centres, from 2007 …
Beschreibung:Commentary on: Coles CE, Griffin CL, Kirby AM, et al. IMPORT Trialists. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet 2017;390:1048–60
Gesehen am 28.02.2020
Beschreibung:Online Resource
ISSN:1473-6810
DOI:10.1136/ebmed-2017-110849

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