Takotsubo syndrome and cardiac implantable electronic device therapy

Recent studies have reported that takotsubo syndrome (TTS) patients are suffering from life-threatening arrhythmias. The aim of our study was to understand the short and long-term usefulness of cardiac implantable electronic devices in TTS patients.We constituted a collective of 142 patients in a bi...

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Main Authors: El-Battrawy, Ibrahim (Author) , Erath-Honold, Julia (Author) , Lang, Siegfried (Author) , Ansari, Uzair (Author) , Behnes, Michael (Author) , Gietzen, Thorsten (Author) , Zhou, Xiao-Bo (Author) , Borggrefe, Martin (Author) , Akın, Ibrahim (Author)
Format: Article (Journal)
Language:English
Published: 12 November 2019
In: Scientific reports
Year: 2019, Volume: 9
ISSN:2045-2322
DOI:10.1038/s41598-019-52929-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41598-019-52929-5
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41598-019-52929-5
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Author Notes:Ibrahim El-Battrawy, Julia W. Erath, Siegfried Lang, Uzair Ansari, Michael Behnes, Thorsten Gietzen, Xiaobo Zhou, Martin Borggrefe & Ibrahim Akin
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Summary:Recent studies have reported that takotsubo syndrome (TTS) patients are suffering from life-threatening arrhythmias. The aim of our study was to understand the short and long-term usefulness of cardiac implantable electronic devices in TTS patients.We constituted a collective of 142 patients in a bi-centric study diagnosed with TTS between 2003 and 2017. The patient groups, divided according to the treatment with (n = 9, 6.3%) or without cardiac devices (n = 133, 93.7%), were followed-up to determine the importance of devices and its complications. One patient was treated with a permanent pacemaker, five patients with a wearable cardioverter defibrillator, two patients with a subcutaneous defibrillator and one patient with a transvenous defibrillator. Regular device check-up was documented in all patients, presenting an ongoing high-degree AV-block. Neither device complications nor life-threatening tachyarrhythmias were documented after acute TTS event. However, patients comprising the device group suffered significantly more often from a highly reduced EF (30 ± 7.7% versus 39.1 ± 9.7%; p < 0.05), cardiogenic shock with use of inotropic agents (66.6% versus 16.6%; p < 0.05) and cardiopulmonary resuscitation (44.4% versus 5.3%; p < 0.05). Our data confirm the usefulness of pacemaker in TTS patients. However, the cardioverter defibrillator including wearable cardioverter defibrillator may not be recommended.
Item Description:Gesehen am 02.03.2020
Physical Description:Online Resource
ISSN:2045-2322
DOI:10.1038/s41598-019-52929-5