Efficient synthesis of indole derivatives containing the tetrazole moeity utilizing an Ugi-azide post-transformation strategy
An efficient strategy has been developed for the synthesis of indole derivatives containing the tetrazole moiety using a AuCl3-catalyzed cyclization reaction. The precursors of the cycloadduct were easily prepared by an Ugi-azide 4-CR in methanol at room temperature. The merit of this protocol lies...
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| Main Authors: | , |
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| Format: | Article (Journal) Editorial |
| Language: | English |
| Published: |
26. Juli 2018
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| In: |
Synlett
Year: 2018, Volume: 29, Issue: 14, Pages: 1892-1896 |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0037-1610502 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1055/s-0037-1610502 Verlag, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610502 
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| Author Notes: | Ali Nikbakht, Saeed Balalaie, Fatemeh Baghestani, Frank Rominger |
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| 520 | |a An efficient strategy has been developed for the synthesis of indole derivatives containing the tetrazole moiety using a AuCl3-catalyzed cyclization reaction. The precursors of the cycloadduct were easily prepared by an Ugi-azide 4-CR in methanol at room temperature. The merit of this protocol lies in its operational simplicity, readily available starting materials, high yields of product, and good functional group tolerance. | ||
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