Efficient synthesis of indole derivatives containing the tetrazole moeity utilizing an Ugi-azide post-transformation strategy
An efficient strategy has been developed for the synthesis of indole derivatives containing the tetrazole moiety using a AuCl3-catalyzed cyclization reaction. The precursors of the cycloadduct were easily prepared by an Ugi-azide 4-CR in methanol at room temperature. The merit of this protocol lies...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
26. Juli 2018
|
| In: |
Synlett
Year: 2018, Jahrgang: 29, Heft: 14, Pages: 1892-1896 |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0037-1610502 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1055/s-0037-1610502 Verlag, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610502 
|
| Verfasserangaben: | Ali Nikbakht, Saeed Balalaie, Fatemeh Baghestani, Frank Rominger |
| Zusammenfassung: | An efficient strategy has been developed for the synthesis of indole derivatives containing the tetrazole moiety using a AuCl3-catalyzed cyclization reaction. The precursors of the cycloadduct were easily prepared by an Ugi-azide 4-CR in methanol at room temperature. The merit of this protocol lies in its operational simplicity, readily available starting materials, high yields of product, and good functional group tolerance. |
|---|---|
| Beschreibung: | Gesehen am 04.03.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0037-1610502 |