Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment
Sarcomas are a heterogeneous group of mesenchymal tumors which can affect bone and soft tissue. Leiomyosarcoma (LMS) is a rare subtype localized to the skin or subcutaneous tissue. Due to the heterogeneity of sarcomas, reviews and guidelines with an in-depth focus specifically on primary LMS of the...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 August 2018
|
| In: |
Medical oncology
Year: 2018, Jahrgang: 35 |
| ISSN: | 1559-131X |
| DOI: | 10.1007/s12032-018-1196-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s12032-018-1196-2
|
| Verfasserangaben: | Martina Zacher, Markus V. Heppt, Titus J. Brinker, Kinan M. Hayani, Michael J. Flaig, Carola Berking |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1691958891 | ||
| 003 | DE-627 | ||
| 005 | 20220818011027.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200310s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s12032-018-1196-2 |2 doi | |
| 035 | |a (DE-627)1691958891 | ||
| 035 | |a (DE-599)KXP1691958891 | ||
| 035 | |a (OCoLC)1341309563 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Zacher, Martina |e VerfasserIn |0 (DE-588)1206199709 |0 (DE-627)1691958840 |4 aut | |
| 245 | 1 | 0 | |a Primary leiomyosarcoma of the skin |b a comprehensive review on diagnosis and treatment |c Martina Zacher, Markus V. Heppt, Titus J. Brinker, Kinan M. Hayani, Michael J. Flaig, Carola Berking |
| 264 | 1 | |c 23 August 2018 | |
| 300 | |a 19 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.03.2020 | ||
| 520 | |a Sarcomas are a heterogeneous group of mesenchymal tumors which can affect bone and soft tissue. Leiomyosarcoma (LMS) is a rare subtype localized to the skin or subcutaneous tissue. Due to the heterogeneity of sarcomas, reviews and guidelines with an in-depth focus specifically on primary LMS of the skin are sparse. This article is intended to provide an up to date and systematic overview on diagnosis, treatment, and surveillance of this rare entity to provide a framework for decision making and management for dermato-oncologists. We discuss novel treatment options for advanced disease such as targeted therapy with kinase inhibitors and immune checkpoint blockade which may improve the prognosis even in advanced stages of LMS. | ||
| 700 | 1 | |a Heppt, Markus V. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Brinker, Titus Josef |d 1990- |e VerfasserIn |0 (DE-588)1156309395 |0 (DE-627)1018860487 |0 (DE-576)502097434 |4 aut | |
| 700 | 1 | |a Hayani, Kinan M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Flaig, Michael J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Berking, Carola |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Medical oncology |d New York, NY : Springer, 1984 |g Band 35.2018, Artikel-Nummer 135, 19 Seiten |h Online-Ressource |w (DE-627)320468240 |w (DE-600)2008172-8 |w (DE-576)288571770 |x 1559-131X |7 nnas |a Primary leiomyosarcoma of the skin a comprehensive review on diagnosis and treatment |
| 773 | 1 | 8 | |g volume:35 |g year:2018 |g extent:19 |a Primary leiomyosarcoma of the skin a comprehensive review on diagnosis and treatment |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s12032-018-1196-2 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200310 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 1156309395 |a Brinker, Titus Josef |m 1156309395:Brinker, Titus Josef |d 50000 |e 50000PB1156309395 |k 0/50000/ | ||
| 999 | |a KXP-PPN1691958891 |e 3605537499 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"origin":[{"dateIssuedKey":"2018","dateIssuedDisp":"23 August 2018"}],"note":["Gesehen am 10.03.2020"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Primary leiomyosarcoma of the skin","subtitle":"a comprehensive review on diagnosis and treatment","title_sort":"Primary leiomyosarcoma of the skin"}],"person":[{"display":"Zacher, Martina","family":"Zacher","role":"aut","given":"Martina"},{"display":"Heppt, Markus V.","family":"Heppt","role":"aut","given":"Markus V."},{"role":"aut","given":"Titus Josef","display":"Brinker, Titus Josef","family":"Brinker"},{"display":"Hayani, Kinan M.","family":"Hayani","role":"aut","given":"Kinan M."},{"role":"aut","given":"Michael J.","family":"Flaig","display":"Flaig, Michael J."},{"role":"aut","given":"Carola","display":"Berking, Carola","family":"Berking"}],"relHost":[{"part":{"text":"Band 35.2018, Artikel-Nummer 135, 19 Seiten","year":"2018","volume":"35","extent":"19"},"title":[{"title":"Medical oncology","title_sort":"Medical oncology"}],"note":["Gesehen am 15.04.14"],"origin":[{"publisher":"Springer ; Humana Press","dateIssuedKey":"1984","publisherPlace":"New York, NY ; Totowa, NJ","dateIssuedDisp":"1984-"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"disp":"Primary leiomyosarcoma of the skin a comprehensive review on diagnosis and treatmentMedical oncology","id":{"zdb":["2008172-8"],"issn":["1559-131X"],"eki":["320468240"]},"physDesc":[{"extent":"Online-Ressource"}],"recId":"320468240","pubHistory":["1.1984 -"]}],"id":{"doi":["10.1007/s12032-018-1196-2"],"eki":["1691958891"]},"recId":"1691958891","name":{"displayForm":["Martina Zacher, Markus V. Heppt, Titus J. Brinker, Kinan M. Hayani, Michael J. Flaig, Carola Berking"]},"physDesc":[{"extent":"19 S."}]} | ||
| SRT | |a ZACHERMARTPRIMARYLEI2320 | ||