7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions
Background: Baló's concentric sclerosis (BCS) is a rare condition characterized by concentrically layered white matter lesions. While its pathogenesis is unknown, hypoxia-induced tissue injury and chemotactic stimuli have been proposed as potential causes of BCS lesion formation. BCS has been...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 June 2018
|
| In: |
Annals of Clinical and Translational Neurology
Year: 2018, Jahrgang: 5, Heft: 8, Pages: 900-912 |
| ISSN: | 2328-9503 |
| DOI: | 10.1002/acn3.572 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/acn3.572 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/acn3.572 
|
| Verfasserangaben: | Janina R. Behrens, Julia Wanner, Joseph Kuchling, Lennard Ostendorf, Lutz Harms, Klemens Ruprecht, Thoralf Niendorf, Sven Jarius, Brigitte Wildemann, René M. Gieß, Michael Scheel, Judith Bellmann‐Strobl, Jens Wuerfel, Friedemann Paul & Tim Sinnecker |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1692000756 | ||
| 003 | DE-627 | ||
| 005 | 20220818011223.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200310s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/acn3.572 |2 doi | |
| 035 | |a (DE-627)1692000756 | ||
| 035 | |a (DE-599)KXP1692000756 | ||
| 035 | |a (OCoLC)1341309906 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Behrens, Janina R. |e VerfasserIn |0 (DE-588)117268345X |0 (DE-627)1041317581 |0 (DE-576)514730862 |4 aut | |
| 240 | 1 | 0 | |a Seven Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions |
| 245 | 1 | 0 | |a 7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions |c Janina R. Behrens, Julia Wanner, Joseph Kuchling, Lennard Ostendorf, Lutz Harms, Klemens Ruprecht, Thoralf Niendorf, Sven Jarius, Brigitte Wildemann, René M. Gieß, Michael Scheel, Judith Bellmann‐Strobl, Jens Wuerfel, Friedemann Paul & Tim Sinnecker |
| 264 | 1 | |c 29 June 2018 | |
| 300 | |a 13 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.03.2020 | ||
| 520 | |a Background: Baló's concentric sclerosis (BCS) is a rare condition characterized by concentrically layered white matter lesions. While its pathogenesis is unknown, hypoxia-induced tissue injury and chemotactic stimuli have been proposed as potential causes of BCS lesion formation. BCS has been suggested to be a variant of multiple sclerosis (MS). Here, we aimed to elucidate similarities and differences between BCS and MS by describing lesion morphology and localization in high-resolution 7 Tesla (7 T) magnetic resonance imaging (MRI) scans. Methods: Ten patients with Baló-type lesions underwent 7 T MRI, and 10 relapsing remitting MS patients served as controls. The 7 T MR imaging protocol included 3D T1-weighted (T1w) magnetization-prepared rapid gradient echo, 2D high spatial resolution T2*-weighted (T2*w) fast low-angle shot and susceptibility-weighted imaging. Results: Intralesional veins were visible in the center of all but one Baló-type lesion. Four Baló-type lesions displayed inhomogeneous intralesional T2*w signal intensities, which are suggestive of microhemorrhages or small ectatic venules. Eight of 10 BCS patients presented with 97 additional lesions, 36 of which (37%) had a central vein. Lesions involving the cortical gray matter and the U-fibers were not detected in BCS patients. Conclusion: Our findings support the hypothesis that BCS and MS share common pathogenetic mechanisms but patients present with different lesion phenotypes. | ||
| 700 | 1 | |a Jarius, Sven |e VerfasserIn |0 (DE-588)1054615918 |0 (DE-627)791654818 |0 (DE-576)410367478 |4 aut | |
| 700 | 1 | |a Wildemann, Brigitte |e VerfasserIn |0 (DE-588)110203844 |0 (DE-627)510150004 |0 (DE-576)171831330 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Annals of Clinical and Translational Neurology |d Chichester [u.a.] : Wiley, 2013 |g 5(2018), 8, Seite 900-912 |h Online-Ressource |w (DE-627)77139649X |w (DE-600)2740696-9 |w (DE-576)396696678 |x 2328-9503 |7 nnas |a 7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions |
| 773 | 1 | 8 | |g volume:5 |g year:2018 |g number:8 |g pages:900-912 |g extent:13 |a 7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions |
| 856 | 4 | 0 | |u https://doi.org/10.1002/acn3.572 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1002/acn3.572 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200310 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 110203844 |a Wildemann, Brigitte |m 110203844:Wildemann, Brigitte |d 910000 |d 911100 |e 910000PW110203844 |e 911100PW110203844 |k 0/910000/ |k 1/910000/911100/ |p 9 | ||
| 998 | |g 1054615918 |a Jarius, Sven |m 1054615918:Jarius, Sven |d 910000 |d 911100 |e 910000PJ1054615918 |e 911100PJ1054615918 |k 0/910000/ |k 1/910000/911100/ |p 8 | ||
| 999 | |a KXP-PPN1692000756 |e 3605619827 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Janina R. Behrens, Julia Wanner, Joseph Kuchling, Lennard Ostendorf, Lutz Harms, Klemens Ruprecht, Thoralf Niendorf, Sven Jarius, Brigitte Wildemann, René M. Gieß, Michael Scheel, Judith Bellmann‐Strobl, Jens Wuerfel, Friedemann Paul & Tim Sinnecker"]},"id":{"eki":["1692000756"],"doi":["10.1002/acn3.572"]},"recId":"1692000756","physDesc":[{"extent":"13 S."}],"titleUni":[{"title":"Seven Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions","title_sort":"Seven Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions"}],"person":[{"family":"Behrens","given":"Janina R.","role":"aut","display":"Behrens, Janina R."},{"display":"Jarius, Sven","family":"Jarius","given":"Sven","role":"aut"},{"given":"Brigitte","role":"aut","family":"Wildemann","display":"Wildemann, Brigitte"}],"relHost":[{"id":{"zdb":["2740696-9"],"issn":["2328-9503"],"eki":["77139649X"]},"title":[{"title_sort":"Annals of Clinical and Translational Neurology","title":"Annals of Clinical and Translational Neurology"}],"part":{"year":"2018","volume":"5","pages":"900-912","extent":"13","text":"5(2018), 8, Seite 900-912","issue":"8"},"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 15.05.20"],"origin":[{"publisherPlace":"Chichester [u.a.]","dateIssuedKey":"2013","dateIssuedDisp":"2013-","publisher":"Wiley"}],"pubHistory":["1.2013 -"],"disp":"7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesionsAnnals of Clinical and Translational Neurology","recId":"77139649X","physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedDisp":"29 June 2018","dateIssuedKey":"2018"}],"title":[{"title":"7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions","title_sort":"7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions"}],"note":["Gesehen am 10.03.2020"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"]} | ||
| SRT | |a BEHRENSJAN7TESLAMRIO2920 | ||