Comparison of three prognostic models for predicting cancer-specific survival among patients with gastrointestinal stromal tumors

Aim: To evaluate the predictive value for cancer-specific survival of the models of the American Joint Committee on Cancer (AJCC) stage, NIH and Armed Forces Institute of Pathology (AFIP) among patients with gastrointestinal stromal tumors (GISTs). Methods: Surveillance, Epidemiology and End Results...

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Hauptverfasser: Oweira, Hani (VerfasserIn) , Schmidt, Jan (VerfasserIn) , Mehrabi, Arianeb (VerfasserIn) , Kulaksiz, Hasan (VerfasserIn) , Schneider, Paul (VerfasserIn) , Schöb, Othmar (VerfasserIn) , Giryes, Anwar (VerfasserIn) , Abdel-Rahman, Omar (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 10 Jan 2018
In: Future oncology
Year: 2018, Jahrgang: 14, Heft: 4, Pages: 379-389
ISSN:1744-8301
DOI:10.2217/fon-2017-0450
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2217/fon-2017-0450
Verlag, lizenzpflichtig, Volltext: https://www.futuremedicine.com/doi/10.2217/fon-2017-0450
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Verfasserangaben:Hani Oweira, Jan Schmidt, Arianeb Mehrabi, Hasan Kulaksiz, Paul Schneider, Othmar Schöb, Anwar Giryes, Omar Abdel-Rahman

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520 |a Aim: To evaluate the predictive value for cancer-specific survival of the models of the American Joint Committee on Cancer (AJCC) stage, NIH and Armed Forces Institute of Pathology (AFIP) among patients with gastrointestinal stromal tumors (GISTs). Methods: Surveillance, Epidemiology and End Results database (2010-2014) was accessed. Overall survival analysis and adjusted cancer-specific Cox regression hazard was calculated. Results: For gastric GISTs, concordance-index according to AJCC was 0.834; according to NIH was 0.833; according to AFIP was 0.836. Concordance-index for nongastric GISTs according to AJCC was 0.800, according to NIH was 0.801 and according to AFIP was 0.799. Conclusion: The performance of the three models is comparable with regards to cancer-specific survival prediction. 
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