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Midostaurin: a multiple tyrosine kinases inhibitor in acute myeloid leukemia and systemic mastocytosis

Midostaurin (PKC412, Rydapt®) is an oral multiple tyrosine kinase inhibitor. Main targets are the kinase domain receptor, vascular endothelial-, platelet derived-, and fibroblast growth factor receptor, stem cell factor receptor c-KIT, as well as mutated and wild-type FLT3 kinases. Midostaurin was a...

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Bibliographic Details
Main Authors: Schlenk, Richard Friedrich (Author) , Kayser, Sabine (Author)
Format: Chapter/Article
Language:English
Published: 2018
In: Small molecules in hematology
Year: 2018, Pages: 199-214
Online Access: Get full text
Author Notes:Richard F. Schlenk, Sabine Kayser

MARC

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