HIV self-test performance among female sex workers in Kampala, Uganda: a cross-sectional study
Objective To evaluate HIV self-testing performance and results interpretation among female sex workers (FSWs) in Kampala, Uganda, who performed unassisted HIV self-testing. - Methods In October 2016, 104 participants used an oral HIV self-test while under observation by research assistants. Particip...
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2018
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| In: |
BMJ open
Year: 2018, Volume: 8, Issue: 11 |
| ISSN: | 2044-6055 |
| DOI: | 10.1136/bmjopen-2018-022652 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/bmjopen-2018-022652 Verlag, lizenzpflichtig, Volltext: https://bmjopen.bmj.com/content/8/11/e022652 
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| Author Notes: | Katrina F. Ortblad, Daniel Kibuuka Musoke, Thomson Ngabirano, Aidah Nakitende, Geoffrey Taasi, Leah G. Barresi, Till Bärnighausen, Catherine E. Oldenburg |
| Summary: | Objective To evaluate HIV self-testing performance and results interpretation among female sex workers (FSWs) in Kampala, Uganda, who performed unassisted HIV self-testing. - Methods In October 2016, 104 participants used an oral HIV self-test while under observation by research assistants. Participants were not assisted on HIV self-test use prior to or during testing, and were only given the manufacturer’s pictorial and written instructions to guide them. Research assistants recorded if participants completed and/or had difficulties with steps in the HIV self-testing process on a prespecified checklist. Randomly drawn, used HIV self-tests were interpreted by FSWs. We calculated the concordance between FSWs’ interpretations of self-test results with those indicated in the manufacturer’s instructions. - Results Only 33% (34/104) of participants completed all of the key steps in the HIV self-testing process, and the majority (86%, 89/104) were observed having difficulties with at least one of these steps. Misinterpretation of HIV self-test results were common among FSWs: 23% (12/56) of FSWs interpreted HIV-negative self-test results as HIV positive and 8% (3/37) of FSWs interpreted HIV-positive self-test results as HIV negative. The concordance between FSWs’ interpretations of self-test results and that indicated in the instructions was 73% (95% CI 56% to 86%) for HIV-positive self-tests and 68% (95% CI 54% to 80%) for HIV-negative self-tests. - Conclusions FSWs in Kampala, who performed unassisted HIV self-testing, skipped steps in the HIV self-testing process and had difficulties correctly interpreting self-test results. Training on use and interpretation of HIV self-tests may be necessary to prevent errors in the HIV self-testing process and to avoid the negative consequences of false-positive and false-negative HIV self-test results among FSWs. - Trial registration number NCT02846402. |
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| Item Description: | Gesehen am 24.03.2020 |
| Physical Description: | Online Resource |
| ISSN: | 2044-6055 |
| DOI: | 10.1136/bmjopen-2018-022652 |