Evaluation of the anti-Thomsen-Friedenreich antibodies Nemod-TF1 and Nemod-TF2 as prognostic markers in breast cancer
The TF (Thomsen-Friedenreich, CD176, Galβ1-3GalNAc) carbohydrate moiety is known as a specific oncofetal carbohydrate epitope present in fetal and neoplastic tissue as well as in stem cells. TF was demonstrated to mediate tumor-promoting features and to be highly immunogenic. The current study aimed...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2020
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| In: |
Breast cancer research and treatment
Year: 2020, Jahrgang: 179, Heft: 3, Pages: 643-652 |
| ISSN: | 1573-7217 |
| DOI: | 10.1007/s10549-019-05503-6 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10549-019-05503-6
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| Verfasserangaben: | Sabine Heublein, Markus Egger, Junyan Zhu, Luisa Berger, Doris Mayr, Christian Schindlbeck, Christina Kuhn, Simone S. Hofmann, Florian Schuetz, Udo Jeschke, Nina Ditsch |
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| 245 | 1 | 0 | |a Evaluation of the anti-Thomsen-Friedenreich antibodies Nemod-TF1 and Nemod-TF2 as prognostic markers in breast cancer |c Sabine Heublein, Markus Egger, Junyan Zhu, Luisa Berger, Doris Mayr, Christian Schindlbeck, Christina Kuhn, Simone S. Hofmann, Florian Schuetz, Udo Jeschke, Nina Ditsch |
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| 520 | |a The TF (Thomsen-Friedenreich, CD176, Galβ1-3GalNAc) carbohydrate moiety is known as a specific oncofetal carbohydrate epitope present in fetal and neoplastic tissue as well as in stem cells. TF was demonstrated to mediate tumor-promoting features and to be highly immunogenic. The current study aimed to evaluate whether presence of the TF antigen is associated with clinico-pathological parameters and prognosis of early breast cancer (BC). | ||
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