Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood
Congenital Zika virus (ZIKV) syndrome may cause fetal microcephaly in ~1% of affected newborns. Here, we investigate whether the majority of clinically inapparent newborns might suffer from long-term health impairments not readily visible at birth. Infection of immunocompetent pregnant mice with hig...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
10 September 2018
|
| In: |
Nature microbiology
Year: 2018, Jahrgang: 3, Heft: 10, Pages: 1161-1174 |
| ISSN: | 2058-5276 |
| DOI: | 10.1038/s41564-018-0236-1 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41564-018-0236-1 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41564-018-0236-1 
|
| Verfasserangaben: | Stephanie Stanelle-Bertram, Kerstin Walendy-Gnirß, Thomas Speiseder, Swantje Thiele, Ivy Asantewaa Asante, Carola Dreier, Nancy Mounogou Kouassi, Annette Preuß, Gundula Pilnitz-Stolze, Ursula Müller, Stefanie Thanisch, Melanie Richter, Robin Scharrenberg, Vanessa Kraus, Ronja Dörk, Lynn Schau, Vanessa Herder, Ingo Gerhauser, Vanessa Maria Pfankuche, Christopher Käufer, Inken Waltl, Thais Moraes, Julie Sellau, Stefan Hoenow, Jonas Schmidt-Chanasit, Stephanie Jansen, Benjamin Schattling, Harald Ittrich, Udo Bartsch, Thomas Renné, Ralf Bartenschlager, Petra Arck, Daniel Cadar, Manuel A. Friese, Olli Vapalahti, Hanna Lotter, Sany Benites, Lane Rolling, Martin Gabriel, Wolfgang Baumgärtner, Fabio Morellini, Sabine M. Hölter, Oana Amarie, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Löscher, Froylan Calderon de Anda, Gülsah Gabriel |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1694243451 | ||
| 003 | DE-627 | ||
| 005 | 20250710224619.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200408s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41564-018-0236-1 |2 doi | |
| 035 | |a (DE-627)1694243451 | ||
| 035 | |a (DE-599)KXP1694243451 | ||
| 035 | |a (OCoLC)1341314279 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Stanelle-Bertram, Stephanie |d 1983- |e VerfasserIn |0 (DE-588)1014375762 |0 (DE-627)666968810 |0 (DE-576)34888785X |4 aut | |
| 245 | 1 | 0 | |a Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood |c Stephanie Stanelle-Bertram, Kerstin Walendy-Gnirß, Thomas Speiseder, Swantje Thiele, Ivy Asantewaa Asante, Carola Dreier, Nancy Mounogou Kouassi, Annette Preuß, Gundula Pilnitz-Stolze, Ursula Müller, Stefanie Thanisch, Melanie Richter, Robin Scharrenberg, Vanessa Kraus, Ronja Dörk, Lynn Schau, Vanessa Herder, Ingo Gerhauser, Vanessa Maria Pfankuche, Christopher Käufer, Inken Waltl, Thais Moraes, Julie Sellau, Stefan Hoenow, Jonas Schmidt-Chanasit, Stephanie Jansen, Benjamin Schattling, Harald Ittrich, Udo Bartsch, Thomas Renné, Ralf Bartenschlager, Petra Arck, Daniel Cadar, Manuel A. Friese, Olli Vapalahti, Hanna Lotter, Sany Benites, Lane Rolling, Martin Gabriel, Wolfgang Baumgärtner, Fabio Morellini, Sabine M. Hölter, Oana Amarie, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Löscher, Froylan Calderon de Anda, Gülsah Gabriel |
| 264 | 1 | |c 10 September 2018 | |
| 300 | |a 48 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 08.04.2020 | ||
| 520 | |a Congenital Zika virus (ZIKV) syndrome may cause fetal microcephaly in ~1% of affected newborns. Here, we investigate whether the majority of clinically inapparent newborns might suffer from long-term health impairments not readily visible at birth. Infection of immunocompetent pregnant mice with high-dose ZIKV caused severe offspring phenotypes, such as fetal death, as expected. By contrast, low-dose (LD) maternal ZIKV infection resulted in reduced fetal birth weight but no other obvious phenotypes. Male offspring born to LD ZIKV-infected mothers had increased testosterone (TST) levels and were less likely to survive in utero infection compared to their female littermates. Males also presented an increased number of immature neurons in apical and basal hippocampal dendrites, while female offspring had immature neurons in basal dendrites only. Moreover, male offspring with high but not very high (storm) TST levels were more likely to suffer from learning and memory impairments compared to females. Future studies are required to understand the impact of TST on neuropathological and neurocognitive impairments in later life. In summary, increased sex-specific vigilance is required in countries with high ZIKV prevalence, where impaired neurodevelopment may be camouflaged by a healthy appearance at birth. | ||
| 650 | 4 | |a Female | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Male | |
| 650 | 4 | |a Animals | |
| 650 | 4 | |a Animals, Newborn | |
| 650 | 4 | |a Brain | |
| 650 | 4 | |a Disease Models, Animal | |
| 650 | 4 | |a Infectious Disease Transmission, Vertical | |
| 650 | 4 | |a Learning Disabilities | |
| 650 | 4 | |a Neurocognitive Disorders | |
| 650 | 4 | |a Placental Insufficiency | |
| 650 | 4 | |a Pregnancy | |
| 650 | 4 | |a Pregnancy Complications, Infectious | |
| 650 | 4 | |a Sex Factors | |
| 650 | 4 | |a Testosterone | |
| 650 | 4 | |a Zika Virus | |
| 650 | 4 | |a Zika Virus Infection | |
| 700 | 1 | |a Walendy-Gnirß, Kerstin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Speiseder, Thomas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Thiele, Swantje |e VerfasserIn |4 aut | |
| 700 | 1 | |a Asante, Ivy Asantewaa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dreier, Carola |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kouassi, Nancy Mounogou |e VerfasserIn |4 aut | |
| 700 | 1 | |a Preuß, Annette |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pilnitz-Stolze, Gundula |e VerfasserIn |4 aut | |
| 700 | 1 | |a Müller, Ursula |e VerfasserIn |4 aut | |
| 700 | 1 | |a Thanisch, Stefanie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Richter, Melanie |d 1971- |e VerfasserIn |0 (DE-588)17354021X |0 (DE-627)698451902 |0 (DE-576)13438458X |4 aut | |
| 700 | 1 | |a Scharrenberg, Robin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kraus, Vanessa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dörk, Ronja |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schau, Lynn |e VerfasserIn |4 aut | |
| 700 | 1 | |8 1\p |a Herder, Vanessa |e VerfasserIn |0 (DE-588)1023387506 |0 (DE-627)718371488 |0 (DE-576)366736035 |4 aut | |
| 700 | 1 | |a Gerhauser, Ingo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pfankuche, Vanessa Maria |e VerfasserIn |4 aut | |
| 700 | 1 | |a Käufer, Christopher |e VerfasserIn |4 aut | |
| 700 | 1 | |a Waltl, Inken |e VerfasserIn |4 aut | |
| 700 | 1 | |a Moraes, Thaís |e VerfasserIn |0 (DE-588)120315982X |0 (DE-627)1687967385 |4 aut | |
| 700 | 1 | |a Sellau, Julie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hoenow, Stefan |e VerfasserIn |4 aut | |
| 700 | 1 | |8 2\p |a Schmidt-Chanasit, Jonas |d 1979- |e VerfasserIn |0 (DE-588)132056534 |0 (DE-627)517457261 |0 (DE-576)298919303 |4 aut | |
| 700 | 1 | |a Jansen, Stephanie |e VerfasserIn |4 aut | |
| 700 | 1 | |8 3\p |a Schattling, Benjamin |e VerfasserIn |0 (DE-588)1156201306 |0 (DE-627)1018680373 |0 (DE-576)50203243X |4 aut | |
| 700 | 1 | |a Ittrich, Harald |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bartsch, Udo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Renné, Thomas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bartenschlager, Ralf |d 1958- |e VerfasserIn |0 (DE-588)1058097989 |0 (DE-627)796390509 |0 (DE-576)168706067 |4 aut | |
| 700 | 1 | |8 4\p |a Arck, Petra |e VerfasserIn |0 (DE-588)1027502946 |0 (DE-627)729241521 |0 (DE-576)172224918 |4 aut | |
| 700 | 1 | |a Cadar, Daniel |e VerfasserIn |4 aut | |
| 700 | 1 | |8 5\p |a Friese, Manuel A. |d 1973- |e VerfasserIn |0 (DE-588)124101151 |0 (DE-627)085638153 |0 (DE-576)294020195 |4 aut | |
| 700 | 1 | |a Vapalahti, Olli |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lotter, Hanna |e VerfasserIn |4 aut | |
| 700 | 1 | |a Benites, Sany |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rolling, Lane |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gabriel, Martin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Baumgärtner, Wolfgang |e VerfasserIn |4 aut | |
| 700 | 1 | |a Morellini, Fabio |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hölter, Sabine M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Amarie, Oana |e VerfasserIn |4 aut | |
| 700 | 1 | |8 6\p |a Fuchs, Helmut |e VerfasserIn |0 (DE-588)1209513757 |0 (DE-627)1697105300 |0 (DE-576)505824140 |4 aut | |
| 700 | 1 | |8 7\p |a Hrabě de Angelis, Martin |d 1964- |e VerfasserIn |0 (DE-588)11436611X |0 (DE-627)50006895X |0 (DE-576)289794811 |4 aut | |
| 700 | 1 | |a Löscher, Wolfgang |e VerfasserIn |4 aut | |
| 700 | 1 | |a Calderon de Anda, Froylan |e VerfasserIn |4 aut | |
| 700 | 1 | |8 8\p |a Gabriel, Gülsah |d 1978- |e VerfasserIn |0 (DE-588)132226200 |0 (DE-627)519544951 |0 (DE-576)299016455 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature microbiology |d London : Nature Publishing Group, 2016 |g 3(2018), 10, Seite 1161-1174 |h Online-Ressource |w (DE-627)846903903 |w (DE-600)2845610-5 |w (DE-576)454971060 |x 2058-5276 |7 nnas |a Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood |
| 773 | 1 | 8 | |g volume:3 |g year:2018 |g number:10 |g pages:1161-1174 |g extent:48 |a Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood |
| 856 | 4 | 0 | |u https://doi.org/10.1038/s41564-018-0236-1 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41564-018-0236-1 |x Verlag |z lizenzpflichtig |3 Volltext |
| 883 | |8 1\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 2\p |a cgwrk |d 20250403 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 3\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 4\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 5\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 6\p |a cgwrk |d 20250701 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 7\p |a cgwrk |d 20250701 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 8\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 951 | |a AR | ||
| 992 | |a 20200408 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 1058097989 |a Bartenschlager, Ralf |m 1058097989:Bartenschlager, Ralf |d 910000 |d 911700 |e 910000PB1058097989 |e 911700PB1058097989 |k 0/910000/ |k 1/910000/911700/ | ||
| 998 | |g 120315982X |a Moraes, Thaís |m 120315982X:Moraes, Thaís |d 910000 |d 911700 |e 910000PM120315982X |e 911700PM120315982X |k 0/910000/ |k 1/910000/911700/ | ||
| 998 | |g 17354021X |a Richter, Melanie |m 17354021X:Richter, Melanie |d 700000 |d 711000 |e 700000PR17354021X |e 711000PR17354021X |k 0/700000/ |k 1/700000/711000/ | ||
| 999 | |a KXP-PPN1694243451 |e 3620375836 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood","title_sort":"Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood"}],"recId":"1694243451","language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"name":{"displayForm":["Stephanie Stanelle-Bertram, Kerstin Walendy-Gnirß, Thomas Speiseder, Swantje Thiele, Ivy Asantewaa Asante, Carola Dreier, Nancy Mounogou Kouassi, Annette Preuß, Gundula Pilnitz-Stolze, Ursula Müller, Stefanie Thanisch, Melanie Richter, Robin Scharrenberg, Vanessa Kraus, Ronja Dörk, Lynn Schau, Vanessa Herder, Ingo Gerhauser, Vanessa Maria Pfankuche, Christopher Käufer, Inken Waltl, Thais Moraes, Julie Sellau, Stefan Hoenow, Jonas Schmidt-Chanasit, Stephanie Jansen, Benjamin Schattling, Harald Ittrich, Udo Bartsch, Thomas Renné, Ralf Bartenschlager, Petra Arck, Daniel Cadar, Manuel A. Friese, Olli Vapalahti, Hanna Lotter, Sany Benites, Lane Rolling, Martin Gabriel, Wolfgang Baumgärtner, Fabio Morellini, Sabine M. Hölter, Oana Amarie, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Löscher, Froylan Calderon de Anda, Gülsah Gabriel"]},"note":["Gesehen am 08.04.2020"],"person":[{"display":"Stanelle-Bertram, Stephanie","role":"aut","given":"Stephanie","roleDisplay":"VerfasserIn","family":"Stanelle-Bertram"},{"given":"Kerstin","role":"aut","display":"Walendy-Gnirß, Kerstin","roleDisplay":"VerfasserIn","family":"Walendy-Gnirß"},{"given":"Thomas","display":"Speiseder, Thomas","role":"aut","roleDisplay":"VerfasserIn","family":"Speiseder"},{"role":"aut","display":"Thiele, Swantje","given":"Swantje","family":"Thiele","roleDisplay":"VerfasserIn"},{"role":"aut","display":"Asante, Ivy Asantewaa","given":"Ivy Asantewaa","family":"Asante","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","family":"Dreier","given":"Carola","role":"aut","display":"Dreier, Carola"},{"roleDisplay":"VerfasserIn","family":"Kouassi","display":"Kouassi, Nancy Mounogou","role":"aut","given":"Nancy Mounogou"},{"display":"Preuß, Annette","role":"aut","given":"Annette","family":"Preuß","roleDisplay":"VerfasserIn"},{"display":"Pilnitz-Stolze, Gundula","role":"aut","given":"Gundula","family":"Pilnitz-Stolze","roleDisplay":"VerfasserIn"},{"display":"Müller, Ursula","role":"aut","given":"Ursula","roleDisplay":"VerfasserIn","family":"Müller"},{"given":"Stefanie","role":"aut","display":"Thanisch, Stefanie","family":"Thanisch","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","family":"Richter","given":"Melanie","display":"Richter, Melanie","role":"aut"},{"role":"aut","display":"Scharrenberg, Robin","given":"Robin","family":"Scharrenberg","roleDisplay":"VerfasserIn"},{"family":"Kraus","roleDisplay":"VerfasserIn","display":"Kraus, Vanessa","role":"aut","given":"Vanessa"},{"given":"Ronja","display":"Dörk, Ronja","role":"aut","family":"Dörk","roleDisplay":"VerfasserIn"},{"family":"Schau","roleDisplay":"VerfasserIn","given":"Lynn","display":"Schau, Lynn","role":"aut"},{"roleDisplay":"VerfasserIn","family":"Herder","display":"Herder, Vanessa","role":"aut","given":"Vanessa"},{"display":"Gerhauser, Ingo","role":"aut","given":"Ingo","family":"Gerhauser","roleDisplay":"VerfasserIn"},{"family":"Pfankuche","roleDisplay":"VerfasserIn","given":"Vanessa Maria","display":"Pfankuche, Vanessa Maria","role":"aut"},{"roleDisplay":"VerfasserIn","family":"Käufer","given":"Christopher","display":"Käufer, Christopher","role":"aut"},{"role":"aut","display":"Waltl, Inken","given":"Inken","family":"Waltl","roleDisplay":"VerfasserIn"},{"role":"aut","display":"Moraes, Thaís","given":"Thaís","family":"Moraes","roleDisplay":"VerfasserIn"},{"family":"Sellau","roleDisplay":"VerfasserIn","given":"Julie","display":"Sellau, Julie","role":"aut"},{"display":"Hoenow, Stefan","role":"aut","given":"Stefan","roleDisplay":"VerfasserIn","family":"Hoenow"},{"family":"Schmidt-Chanasit","roleDisplay":"VerfasserIn","role":"aut","display":"Schmidt-Chanasit, Jonas","given":"Jonas"},{"family":"Jansen","roleDisplay":"VerfasserIn","given":"Stephanie","role":"aut","display":"Jansen, Stephanie"},{"given":"Benjamin","display":"Schattling, Benjamin","role":"aut","family":"Schattling","roleDisplay":"VerfasserIn"},{"family":"Ittrich","roleDisplay":"VerfasserIn","role":"aut","display":"Ittrich, Harald","given":"Harald"},{"family":"Bartsch","roleDisplay":"VerfasserIn","given":"Udo","display":"Bartsch, Udo","role":"aut"},{"family":"Renné","roleDisplay":"VerfasserIn","given":"Thomas","role":"aut","display":"Renné, Thomas"},{"roleDisplay":"VerfasserIn","family":"Bartenschlager","given":"Ralf","display":"Bartenschlager, Ralf","role":"aut"},{"family":"Arck","roleDisplay":"VerfasserIn","display":"Arck, Petra","role":"aut","given":"Petra"},{"given":"Daniel","display":"Cadar, Daniel","role":"aut","family":"Cadar","roleDisplay":"VerfasserIn"},{"family":"Friese","roleDisplay":"VerfasserIn","given":"Manuel A.","role":"aut","display":"Friese, Manuel A."},{"display":"Vapalahti, Olli","role":"aut","given":"Olli","roleDisplay":"VerfasserIn","family":"Vapalahti"},{"family":"Lotter","roleDisplay":"VerfasserIn","display":"Lotter, Hanna","role":"aut","given":"Hanna"},{"role":"aut","display":"Benites, Sany","given":"Sany","roleDisplay":"VerfasserIn","family":"Benites"},{"display":"Rolling, Lane","role":"aut","given":"Lane","family":"Rolling","roleDisplay":"VerfasserIn"},{"family":"Gabriel","roleDisplay":"VerfasserIn","display":"Gabriel, Martin","role":"aut","given":"Martin"},{"family":"Baumgärtner","roleDisplay":"VerfasserIn","display":"Baumgärtner, Wolfgang","role":"aut","given":"Wolfgang"},{"family":"Morellini","roleDisplay":"VerfasserIn","role":"aut","display":"Morellini, Fabio","given":"Fabio"},{"roleDisplay":"VerfasserIn","family":"Hölter","given":"Sabine M.","role":"aut","display":"Hölter, Sabine M."},{"given":"Oana","display":"Amarie, Oana","role":"aut","roleDisplay":"VerfasserIn","family":"Amarie"},{"family":"Fuchs","roleDisplay":"VerfasserIn","given":"Helmut","role":"aut","display":"Fuchs, Helmut"},{"roleDisplay":"VerfasserIn","family":"Hrabě de Angelis","display":"Hrabě de Angelis, Martin","role":"aut","given":"Martin"},{"given":"Wolfgang","display":"Löscher, Wolfgang","role":"aut","roleDisplay":"VerfasserIn","family":"Löscher"},{"role":"aut","display":"Calderon de Anda, Froylan","given":"Froylan","family":"Calderon de Anda","roleDisplay":"VerfasserIn"},{"role":"aut","display":"Gabriel, Gülsah","given":"Gülsah","family":"Gabriel","roleDisplay":"VerfasserIn"}],"physDesc":[{"extent":"48 S."}],"id":{"doi":["10.1038/s41564-018-0236-1"],"eki":["1694243451"]},"relHost":[{"pubHistory":["Volume 1, issue 1 (January 2016)-"],"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"part":{"extent":"48","issue":"10","volume":"3","year":"2018","text":"3(2018), 10, Seite 1161-1174","pages":"1161-1174"},"disp":"Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthoodNature microbiology","title":[{"title":"Nature microbiology","title_sort":"Nature microbiology"}],"recId":"846903903","id":{"zdb":["2845610-5"],"eki":["846903903"],"issn":["2058-5276"]},"origin":[{"publisher":"Nature Publishing Group","dateIssuedDisp":"[2016]-","publisherPlace":"London"}],"note":["Gesehen am 12.02.18"],"physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedDisp":"10 September 2018","dateIssuedKey":"2018"}]} | ||
| SRT | |a STANELLEBEMALEOFFSPR1020 | ||