Schistosoma mansoni egg-secreted antigens activate hepatocellular carcinoma-associated transcription factors c‐Jun and STAT3 in hamster and human hepatocytes

Clinical data have provided evidence that schistosomiasis can promote hepatocellular carcinogenesis. c‐Jun and STAT3 are critical regulators of liver cancer development and progression. The aim of th...

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Bibliographic Details
Main Authors: Roderfeld, Martin (Author) , Longerich, Thomas (Author)
Format: Article (Journal)
Language:English
Published: [2020]
In: Hepatology
Year: 2018, Volume: 72, Issue: 2, Pages: 626-641
ISSN:1527-3350
DOI:10.1002/hep.30192
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/hep.30192
Verlag, lizenzpflichtig, Volltext: https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.30192
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Author Notes:Martin Roderfeld, Sevinc Padem, Jakob Lichtenberger, Thomas Quack, Ralf Weiskirchen, Thomas Longerich, Gabriele Schramm, Yuri Churin, Karuna Irungbam, Annette Tschuschner, Anita Windhorst, Christoph G. Grevelding, and Elke Roeb
Description
Summary:Clinical data have provided evidence that schistosomiasis can promote hepatocellular carcinogenesis. c‐Jun and STAT3 are critical regulators of liver cancer development and progression. The aim of th...
Item Description:Version of record online: 12 February 2019
First published: 27 July 2018
Gesehen am 25.09.2020
Physical Description:Online Resource
ISSN:1527-3350
DOI:10.1002/hep.30192