DNA nanotechnology for building artificial dynamic systems

A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical energy into mechanical work. They coexist in every eukaryotic cel...

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Bibliographic Details
Main Author: Liu, Na (Author)
Format: Article (Journal)
Language:English
Published: 12 July 2019
In: MRS bulletin
Year: 2019, Volume: 44, Issue: 7, Pages: 576-581
ISSN:1938-1425
DOI:10.1557/mrs.2019.155
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1557/mrs.2019.155
Verlag, lizenzpflichtig, Volltext: https://www.cambridge.org/core/journals/mrs-bulletin/article/dna-nanotechnology-for-building-artificial-dynamic-systems/3851C9EEBEAD09779441BF27E217B975
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Author Notes:Na Liu

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520 |a A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical energy into mechanical work. They coexist in every eukaryotic cell, but differ in their types of motion, the filaments they bind to, the cargos they carry, as well as the work they perform. Such natural structures offer inspiration and blueprints for constructing DNA-assembled artificial systems, which mimic their functionality. In this article, we describe two groups of cytoskeletal motors, linear and rotary motors. We discuss how their artificial analogues can be built using DNA nanotechnology. Finally, we summarize ongoing research directions and conclude that DNA origami has a bright future ahead. 
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