RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML
Key Points. Germline RUNX1 mutations lead to significant phenotypic heterogeneity in families.Germline RUNX1-mutated acute myeloid leukemia has a different som
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 March 2020
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| In: |
Blood advances
Year: 2020, Jahrgang: 4, Heft: 6, Pages: 1131-1144 |
| ISSN: | 2473-9537 |
| DOI: | 10.1182/bloodadvances.2019000901 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/bloodadvances.2019000901 Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/bloodadvances/article/4/6/1131/452758/RUNX1-mutated-families-show-phenotype 
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| Verfasserangaben: | Anna L. Brown, Peer Arts, Catherine L. Carmichael, Milena Babic, Julia Dobbins, Chan-Eng Chong, Andreas W. Schreiber, Jinghua Feng, Kerry Phillips, Paul P. S. Wang, Thuong Ha, Claire C. Homan, Sarah L. King-Smith, Lesley Rawlings, Cassandra Vakulin, Andrew Dubowsky, Jessica Burdett, Sarah Moore, Grace McKavanagh, Denae Henry, Amanda Wells, Belinda Mercorella, Mario Nicola, Jeffrey Suttle, Ella Wilkins, Xiao-Chun Li, Joelle Michaud, Peter Brautigan, Ping Cannon, Meryl Altree, Louise Jaensch, Miriam Fine, Carolyn Butcher, Richard J. D’Andrea, Ian D. Lewis, Devendra K. Hiwase, Elli Papaemmanuil, Marshall S. Horwitz, Georges Natsoulis, Hugh Y. Rienhoff, Nigel Patton, Sally Mapp, Rachel Susman, Susan Morgan, Julian Cooney, Mark Currie, Uday Popat, Tilmann Bochtler, Shai Izraeli, Kenneth Bradstock, Lucy A. Godley, Alwin Krämer, Stefan Fröhling, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Nicola K. Poplawski, Christopher N. Hahn, and Hamish S. Scott |
| Zusammenfassung: | Key Points. Germline RUNX1 mutations lead to significant phenotypic heterogeneity in families.Germline RUNX1-mutated acute myeloid leukemia has a different som |
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| Beschreibung: | Gesehen am 23.04.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 2473-9537 |
| DOI: | 10.1182/bloodadvances.2019000901 |