Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment
Metastatic spinal cord compression (MSCC) is a frequent phenomenon in advanced tumor diseases with often severe neurological impairments. Affected patients are often treated by decompressive laminectomy. To assess the impact of this procedure on Karnofsky Performance Index (KPI) and Frankel Grade (F...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 January 2020
|
| In: |
Clinical & experimental metastasis
Year: 2020, Jahrgang: 37, Heft: 2, Pages: 377-390 |
| ISSN: | 1573-7276 |
| DOI: | 10.1007/s10585-019-10016-z |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10585-019-10016-z
|
| Verfasserangaben: | Alexander Younsi, Lennart Riemann, Moritz Scherer, Andreas Unterberg, Klaus Zweckberger |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1696074568 | ||
| 003 | DE-627 | ||
| 005 | 20240405193243.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200424s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10585-019-10016-z |2 doi | |
| 035 | |a (DE-627)1696074568 | ||
| 035 | |a (DE-599)KXP1696074568 | ||
| 035 | |a (OCoLC)1341316862 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Younsi, Alexander |d 1985- |e VerfasserIn |0 (DE-588)104607508X |0 (DE-627)775681547 |0 (DE-576)39935882X |4 aut | |
| 245 | 1 | 0 | |a Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment |c Alexander Younsi, Lennart Riemann, Moritz Scherer, Andreas Unterberg, Klaus Zweckberger |
| 264 | 1 | |c 20 January 2020 | |
| 300 | |a 14 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 24.04.2020 | ||
| 520 | |a Metastatic spinal cord compression (MSCC) is a frequent phenomenon in advanced tumor diseases with often severe neurological impairments. Affected patients are often treated by decompressive laminectomy. To assess the impact of this procedure on Karnofsky Performance Index (KPI) and Frankel Grade (FG) at discharge, a single center retrospective cohort study of neurologically impaired MSCC-patients treated with decompressive laminectomy between 2004 and 2014 was performed. 101 patients (27 female/74 male; age 66.1 ± 11.5 years) were identified. Prostate was the most common primary tumor site (40%) and progressive disease was present in 74%. At admission, 80% of patients were non-ambulatory (FG A-C). Imaging revealed prevalently thoracic MSCC (78%). Emergency surgery (< 24 h) was performed in 71% and rates of complications and revision surgery were 6% and 4%, respectively. At discharge, FG had improved in 61% of cases, and 51% of patients had regained ambulation. Univariate predictors for not regaining the ability to walk were bowl dysfunction (p = 0.0015), KPI < 50% (p = 0.048) and FG < C (p = 0.001) prior to surgery. In conclusion, decompressive laminectomy showed beneficial effects on the functional outcome at discharge. A good neurological status prior to surgery was key predictor for a good functional outcome. | ||
| 700 | 1 | |a Riemann, Lennart |e VerfasserIn |0 (DE-588)1199567108 |0 (DE-627)1681875551 |4 aut | |
| 700 | 1 | |a Scherer, Moritz |d 1984- |e VerfasserIn |0 (DE-588)1026157684 |0 (DE-627)726207845 |0 (DE-576)371433983 |4 aut | |
| 700 | 1 | |a Unterberg, Andreas |e VerfasserIn |0 (DE-588)1032681187 |0 (DE-627)738641200 |0 (DE-576)168441233 |4 aut | |
| 700 | 1 | |a Zweckberger, Klaus |d 1978- |e VerfasserIn |0 (DE-588)13205034X |0 (DE-627)517299534 |0 (DE-576)298915510 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical & experimental metastasis |d Dordrecht : Springer Science + Business Media B.V., 1983 |g 37(2020), 2, Seite 377-390 |h Online-Ressource |w (DE-627)306354683 |w (DE-600)1496876-9 |w (DE-576)121190714 |x 1573-7276 |7 nnas |a Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment |
| 773 | 1 | 8 | |g volume:37 |g year:2020 |g number:2 |g pages:377-390 |g extent:14 |a Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10585-019-10016-z |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200424 | ||
| 993 | |a Article | ||
| 994 | |a 2010 | ||
| 998 | |g 13205034X |a Zweckberger, Klaus |m 13205034X:Zweckberger, Klaus |d 910000 |d 911200 |e 910000PZ13205034X |e 911200PZ13205034X |k 0/910000/ |k 1/910000/911200/ |p 5 |y j | ||
| 998 | |g 1032681187 |a Unterberg, Andreas |m 1032681187:Unterberg, Andreas |d 910000 |d 911200 |e 910000PU1032681187 |e 911200PU1032681187 |k 0/910000/ |k 1/910000/911200/ |p 4 | ||
| 998 | |g 1026157684 |a Scherer, Moritz |m 1026157684:Scherer, Moritz |d 910000 |d 911200 |e 910000PS1026157684 |e 911200PS1026157684 |k 0/910000/ |k 1/910000/911200/ |p 3 | ||
| 998 | |g 1199567108 |a Riemann, Lennart |m 1199567108:Riemann, Lennart |d 50000 |e 50000PR1199567108 |k 0/50000/ |p 2 | ||
| 998 | |g 104607508X |a Younsi, Alexander |m 104607508X:Younsi, Alexander |d 910000 |d 911200 |e 910000PY104607508X |e 911200PY104607508X |k 0/910000/ |k 1/910000/911200/ |p 1 |x j | ||
| 999 | |a KXP-PPN1696074568 |e 3633314873 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"origin":[{"dateIssuedDisp":"20 January 2020","dateIssuedKey":"2020"}],"note":["Gesehen am 24.04.2020"],"recId":"1696074568","relHost":[{"id":{"issn":["1573-7276"],"zdb":["1496876-9"],"eki":["306354683"]},"language":["eng"],"recId":"306354683","pubHistory":["1.1983 -"],"note":["Gesehen am"],"origin":[{"publisherPlace":"Dordrecht ; Dordrecht [u.a.]","dateIssuedKey":"1983","dateIssuedDisp":"1983-","publisher":"Springer Science + Business Media B.V. ; Kluwer"}],"disp":"Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairmentClinical & experimental metastasis","physDesc":[{"extent":"Online-Ressource"}],"title":[{"subtitle":"official journal of the Metastasis Research Society","title":"Clinical & experimental metastasis","title_sort":"Clinical & experimental metastasis"}],"part":{"volume":"37","extent":"14","issue":"2","year":"2020","pages":"377-390","text":"37(2020), 2, Seite 377-390"},"type":{"bibl":"periodical","media":"Online-Ressource"},"titleAlt":[{"title":"Clinical & experimental metastasis"},{"title":"Clinical and experimental metastasis"}]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"name":{"displayForm":["Alexander Younsi, Lennart Riemann, Moritz Scherer, Andreas Unterberg, Klaus Zweckberger"]},"language":["eng"],"title":[{"title_sort":"Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment","title":"Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment"}],"person":[{"given":"Alexander","display":"Younsi, Alexander","role":"aut","family":"Younsi"},{"family":"Riemann","display":"Riemann, Lennart","given":"Lennart","role":"aut"},{"display":"Scherer, Moritz","given":"Moritz","role":"aut","family":"Scherer"},{"role":"aut","display":"Unterberg, Andreas","given":"Andreas","family":"Unterberg"},{"role":"aut","display":"Zweckberger, Klaus","given":"Klaus","family":"Zweckberger"}],"id":{"doi":["10.1007/s10585-019-10016-z"],"eki":["1696074568"]},"physDesc":[{"extent":"14 S."}]} | ||
| SRT | |a YOUNSIALEXIMPACTOFDE2020 | ||