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Tspan8-tumor extracellular vesicle-induced endothelial cell and fibroblast remodeling relies on the target cell-selective response

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Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment. TEX-promoted target reprogramming is still being disputed, we explored rat endothelial cell (EC) and lung fibroblas...

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Main Authors: Mu, Wei (Author) , Provaznik, Jan (Author) , Hackert, Thilo (Author) , Zöller, Margot (Author)
Format: Article (Journal)
Language:English
Published: 29 January 2020
In: Cells
Year: 2020, Volume: 9, Issue: 2
ISSN:2073-4409
DOI:10.3390/cells9020319
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cells9020319
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2073-4409/9/2/319
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Author Notes:Wei Mu, Jan Provaznik, Thilo Hackert and Margot Zöller
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Placenta-specific 8 is overexpressed and regulates cell proliferation in low-grade human pancreatic neuroendocrine tumors by Tatura, Marina (Author) , Schmidt, Harald (Author) , Haijat, Mikail (Author) , Stark, Maren (Author) , Rinke, Anja (Author) , Diels, Ramon (Author) , Lawlor, Rita T. (Author) , Scarpa, Aldo (Author) , Schrader, Jörg (Author) , Hackert, Thilo (Author) , Schimmack, Simon (Author) , Gress, Thomas Mathias (Author) , Buchholz, Malte (Author) ,


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