Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling
Background: Surgical treatment of endocrine orbitopathy can be performed by way of resecting orbital walls, which effectively releases superfluous tissue from the surgically enlarged orbital space allowing the eyeballs to move back. Existing approaches aim to select an optimal surgical strategy base...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2020
|
| In: |
Clinical biomechanics
Year: 2019, Volume: 71, Pages: 86-91 |
| ISSN: | 1879-1271 |
| DOI: | 10.1016/j.clinbiomech.2019.10.015 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.clinbiomech.2019.10.015 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0268003319300786 
|
| Author Notes: | Evgeny Gladilin, Thomas Hierl, Ina Sterker, Heike Hümpfner-Hierl, Alexander Hemprich, Matthias Krause |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1696684331 | ||
| 003 | DE-627 | ||
| 005 | 20220818055511.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200428r20202019xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.clinbiomech.2019.10.015 |2 doi | |
| 035 | |a (DE-627)1696684331 | ||
| 035 | |a (DE-599)KXP1696684331 | ||
| 035 | |a (OCoLC)1341317263 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Gladilin, Evgeny |e VerfasserIn |0 (DE-588)1162502290 |0 (DE-627)1026599474 |0 (DE-576)348573685 |4 aut | |
| 245 | 1 | 0 | |a Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling |c Evgeny Gladilin, Thomas Hierl, Ina Sterker, Heike Hümpfner-Hierl, Alexander Hemprich, Matthias Krause |
| 264 | 1 | |c 2020 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Available online: 29 October 2019 | ||
| 500 | |a Gesehen am 28.04.2020 | ||
| 520 | |a Background: Surgical treatment of endocrine orbitopathy can be performed by way of resecting orbital walls, which effectively releases superfluous tissue from the surgically enlarged orbital space allowing the eyeballs to move back. Existing approaches aim to select an optimal surgical strategy based on statistical correlations between the extent of the surgical procedure and the resulting bulbus displacement but do not provide an individual surgery plan or predict surgery outcome. - Methods: In this retrospective study, we performed a quantitative analysis of pre- and post-surgery 3D tomographic data of six patients and applied explorative biomechanical modeling of orbital mechanics to dissect factors influencing patient-specific outcome. - Findings: Our experimental results showed a large variability of the backward eyeball displacement in dependency on the amount of orbital volume flow, which could partially be described by computational simulation. Our detailed analysis revealed that patients with regular fat tissue show a good correlation between bulbus displacement and relative volume of decompressed tissue, which, in turn, correlates with decrease in hydrostatic pressure. In contrast, patients with fibrotic tissue exhibit significantly reduced and computationally less predictable eyeball translation in response to surgical tissue decompression. - Interpretation: Based on the results of this study we see a great potential for quantitative planning of surgical exophthalmos treatment using 3D biomechanical modeling. Conventional approaches to planning of soft tissue interventions consider, however, only the patient's 3D anatomy and widely disregard individual tissue properties. Further investigations are required to establish reliable procedures for assessment of individual tissue properties and incorporating them into patient-specific models of orbital mechanics. | ||
| 534 | |c 2019 | ||
| 650 | 4 | |a 3D anatomical modeling | |
| 650 | 4 | |a Biomechanical simulation | |
| 650 | 4 | |a Computer-assisted surgery planning | |
| 650 | 4 | |a Endocrine orbitopathy | |
| 650 | 4 | |a Fibrosis | |
| 650 | 4 | |a Retrospective cohort study | |
| 700 | 1 | |a Hierl, Thomas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sterker, Ina |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hümpfner-Hierl, Heike |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hemprich, Alexander |e VerfasserIn |4 aut | |
| 700 | 1 | |a Krause, Matthias |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical biomechanics |d Amsterdam [u.a.] : Elsevier Science, 1986 |g 71(2020), Seite 86-91 |h Online-Ressource |w (DE-627)32043740X |w (DE-600)2004518-9 |w (DE-576)261823612 |x 1879-1271 |7 nnas |a Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling |
| 773 | 1 | 8 | |g volume:71 |g year:2020 |g pages:86-91 |g extent:6 |a Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.clinbiomech.2019.10.015 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0268003319300786 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200428 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 1162502290 |a Gladilin, Evgeny |m 1162502290:Gladilin, Evgeny |d 700000 |d 716000 |e 700000PG1162502290 |e 716000PG1162502290 |k 0/700000/ |k 1/700000/716000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1696684331 |e 3639805321 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title_sort":"Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling","title":"Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modeling"}],"person":[{"given":"Evgeny","family":"Gladilin","role":"aut","display":"Gladilin, Evgeny","roleDisplay":"VerfasserIn"},{"family":"Hierl","given":"Thomas","roleDisplay":"VerfasserIn","display":"Hierl, Thomas","role":"aut"},{"given":"Ina","family":"Sterker","role":"aut","display":"Sterker, Ina","roleDisplay":"VerfasserIn"},{"given":"Heike","family":"Hümpfner-Hierl","role":"aut","roleDisplay":"VerfasserIn","display":"Hümpfner-Hierl, Heike"},{"display":"Hemprich, Alexander","roleDisplay":"VerfasserIn","role":"aut","family":"Hemprich","given":"Alexander"},{"family":"Krause","given":"Matthias","display":"Krause, Matthias","roleDisplay":"VerfasserIn","role":"aut"}],"language":["eng"],"recId":"1696684331","note":["Available online: 29 October 2019","Gesehen am 28.04.2020"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"doi":["10.1016/j.clinbiomech.2019.10.015"],"eki":["1696684331"]},"origin":[{"dateIssuedDisp":"2020","dateIssuedKey":"2020"}],"name":{"displayForm":["Evgeny Gladilin, Thomas Hierl, Ina Sterker, Heike Hümpfner-Hierl, Alexander Hemprich, Matthias Krause"]},"relHost":[{"title":[{"title_sort":"Clinical biomechanics","subtitle":"a journal affiliated to the International Society of Biomechanics and the American Society of Biomechanics","title":"Clinical biomechanics"}],"language":["eng"],"recId":"32043740X","disp":"Retrospective cohort study of three-wall orbital resection for treatment of endocrine orbitopathy using 3D tomographic data and biomechanical modelingClinical biomechanics","note":["Gesehen am 04.02.20"],"type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"volume":"71","text":"71(2020), Seite 86-91","extent":"6","year":"2020","pages":"86-91"},"pubHistory":["1.1986 -"],"id":{"issn":["1879-1271"],"zdb":["2004518-9"],"eki":["32043740X"]},"origin":[{"dateIssuedDisp":"1986-","dateIssuedKey":"1986","publisher":"Elsevier Science","publisherPlace":"Amsterdam [u.a.]"}],"physDesc":[{"extent":"Online-Ressource"}]}],"physDesc":[{"extent":"6 S."}]} | ||
| SRT | |a GLADILINEVRETROSPECT2020 | ||