Human cytomegalovirus glycoprotein B inhibits migration of breast cancer MDA‑MB‑231 cells and impairs TGF‑β/Smad2/3 expression
Breast cancer is a leading cause of cancer‑associated mortality in females worldwide and evidence suggests that human cytomegalovirus (HCMV) infection may be implicated in the progress of breast cancer. HCMV glycoprotein B (gB) is the most abundant envelope protein and serves an important role in ho...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 23, 2018
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| In: |
Oncology letters
Year: 2018, Jahrgang: 15, Heft: 5, Pages: 7730-7738 |
| ISSN: | 1792-1082 |
| DOI: | 10.3892/ol.2018.8344 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3892/ol.2018.8344 Verlag, lizenzpflichtig, Volltext: http://www.spandidos-publications.com/10.3892/ol.2018.8344/abstract |
| Verfasserangaben: | Rui Yang, Jie Liang, Guo-Xiong Xu, Liu-Mei Ding, Hong-Mei Huang, Qi-Zhu Su, Jing Yan and Yun-Chun Li |
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| 520 | |a Breast cancer is a leading cause of cancer‑associated mortality in females worldwide and evidence suggests that human cytomegalovirus (HCMV) infection may be implicated in the progress of breast cancer. HCMV glycoprotein B (gB) is the most abundant envelope protein and serves an important role in host cell entry. The present study aimed to clarify the role of HCMV gB in breast cancer cells. | ||
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