Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio
Abstract. The accumulation of mutations is frequently associated with alterations in gene function leading to the onset of diseases, including cancer. Aiming t
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2020
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| In: |
Nucleic acids research
Year: 2019, Jahrgang: 48, Heft: 1, Pages: 264-277 |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkz1006 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/nar/gkz1006 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/nar/article/48/1/264/5606628 
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| Verfasserangaben: | Tobias T. Schmidt, Sushma Sharma, Gloria X. Reyes, Anna Kolodziejczak, Tina Wagner, Brian Luke, Anders Hofer, Andrei Chabes and Hans Hombauer |
| Zusammenfassung: | Abstract. The accumulation of mutations is frequently associated with alterations in gene function leading to the onset of diseases, including cancer. Aiming t |
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| Beschreibung: | Published online 24 October 2019 Gesehen am 29.04.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkz1006 |