Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma
The genetic hallmark of Burkitt lymphoma (BL) is a translocation juxtaposing the MYC-oncogene to one of the three immunoglobulin (IG) loci.[1][1] There is ongoing controversy whether IG- MYC negative “true” BL exist. Various studies have identified 2-22% of BL as “ MYC -negative”.[2][2]-[5
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2020
|
| In: |
Haematologica
Year: 2020, Jahrgang: 105, Heft: 4, Pages: e202-e205 |
| ISSN: | 1592-8721 |
| DOI: | 10.3324/haematol.2018.208140 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3324/haematol.2018.208140 Verlag, lizenzpflichtig, Volltext: http://www.haematologica.org/content/105/4/e202 
|
| Verfasserangaben: | Rabea Wagener, Susanne Bens, Umut H. Toprak, Julian Seufert, Cristina López, Ingrid Scholz, Heidi Herbrueggen, Ilske Oschlies, Stephan Stilgenbauer, Matthias Schlesner, Wolfram Klapper, Birgit Burkhardt and Reiner Siebert |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1696847982 | ||
| 003 | DE-627 | ||
| 005 | 20220818061814.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200429s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3324/haematol.2018.208140 |2 doi | |
| 035 | |a (DE-627)1696847982 | ||
| 035 | |a (DE-599)KXP1696847982 | ||
| 035 | |a (OCoLC)1341317687 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Wagener, Rabea |e VerfasserIn |0 (DE-588)1123217793 |0 (DE-627)876562594 |0 (DE-576)481668314 |4 aut | |
| 245 | 1 | 0 | |a Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma |c Rabea Wagener, Susanne Bens, Umut H. Toprak, Julian Seufert, Cristina López, Ingrid Scholz, Heidi Herbrueggen, Ilske Oschlies, Stephan Stilgenbauer, Matthias Schlesner, Wolfram Klapper, Birgit Burkhardt and Reiner Siebert |
| 246 | 3 | 0 | |a two three |
| 264 | 1 | |c 2020 | |
| 300 | |a 4 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.04.2020 | ||
| 520 | |a The genetic hallmark of Burkitt lymphoma (BL) is a translocation juxtaposing the MYC-oncogene to one of the three immunoglobulin (IG) loci.[1][1] There is ongoing controversy whether IG- MYC negative “true” BL exist. Various studies have identified 2-22% of BL as “ MYC -negative”.[2][2]-[5 | ||
| 700 | 1 | |a Toprak, Umut |d 1986- |e VerfasserIn |0 (DE-588)1201204429 |0 (DE-627)1684659019 |4 aut | |
| 700 | 1 | |a Seufert, Julian |d 1992- |e VerfasserIn |0 (DE-588)1209283344 |0 (DE-627)1696930227 |4 aut | |
| 700 | 1 | |a Schlesner, Matthias |d 1978- |e VerfasserIn |0 (DE-588)138455201 |0 (DE-627)602593867 |0 (DE-576)307654656 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Haematologica |d Pavia : Ferrata Storti Foundation, 2014 |g 105(2020), 4, Seite e202-e205 |h Online-Ressource |w (DE-627)814204899 |w (DE-600)2805244-4 |w (DE-576)424051125 |x 1592-8721 |7 nnas |a Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma |
| 773 | 1 | 8 | |g volume:105 |g year:2020 |g number:4 |g pages:e202-e205 |g extent:4 |a Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma |
| 856 | 4 | 0 | |u https://doi.org/10.3324/haematol.2018.208140 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.haematologica.org/content/105/4/e202 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200429 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 1209283344 |a Seufert, Julian |m 1209283344:Seufert, Julian |d 140000 |e 140000PS1209283344 |k 0/140000/ |p 4 | ||
| 998 | |g 138455201 |a Schlesner, Matthias |m 138455201:Schlesner, Matthias |d 140000 |e 140000PS138455201 |k 0/140000/ |p 10 | ||
| 998 | |g 1201204429 |a Toprak, Umut |m 1201204429:Toprak, Umut |p 3 | ||
| 999 | |a KXP-PPN1696847982 |e 3643344406 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma","title_sort":"Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma"}],"language":["eng"],"person":[{"role":"aut","given":"Rabea","display":"Wagener, Rabea","family":"Wagener"},{"family":"Toprak","display":"Toprak, Umut","given":"Umut","role":"aut"},{"family":"Seufert","role":"aut","given":"Julian","display":"Seufert, Julian"},{"family":"Schlesner","given":"Matthias","role":"aut","display":"Schlesner, Matthias"}],"name":{"displayForm":["Rabea Wagener, Susanne Bens, Umut H. Toprak, Julian Seufert, Cristina López, Ingrid Scholz, Heidi Herbrueggen, Ilske Oschlies, Stephan Stilgenbauer, Matthias Schlesner, Wolfram Klapper, Birgit Burkhardt and Reiner Siebert"]},"id":{"eki":["1696847982"],"doi":["10.3324/haematol.2018.208140"]},"physDesc":[{"extent":"4 S."}],"note":["Gesehen am 29.04.2020"],"relHost":[{"language":["eng"],"part":{"volume":"105","year":"2020","text":"105(2020), 4, Seite e202-e205","issue":"4","extent":"4","pages":"e202-e205"},"title":[{"title_sort":"Haematologica","subtitle":"journal of the European Hematology Association : journal of the Ferrata Storti Foundation","title":"Haematologica"}],"pubHistory":["99.2014 -"],"note":["Gesehen am 27.05.2022"],"disp":"Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphomaHaematologica","id":{"zdb":["2805244-4"],"issn":["1592-8721"],"eki":["814204899"]},"physDesc":[{"extent":"Online-Ressource"}],"titleAlt":[{"title":"journal of the European Hematology Association"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"814204899","origin":[{"publisher":"Ferrata Storti Foundation","dateIssuedDisp":"2014-","dateIssuedKey":"2014","publisherPlace":"Pavia"}]}],"origin":[{"dateIssuedKey":"2020","dateIssuedDisp":"2020"}],"recId":"1696847982","type":{"media":"Online-Ressource","bibl":"article-journal"}} | ||
| SRT | |a WAGENERRABCRYPTICINS2020 | ||