Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation

Amiodarone is a frequently used antiarrhythmic drug in patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been controversially discussed, with divergent results regarding morbidity and mortality after heart transplantation (HTX).Aim: The aim of thi...

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Main Authors: Rivinius, Rasmus (Author) , Helmschrott, Matthias (Author) , Ruhparwar, Arjang (Author) , Schmack, Bastian (Author) , Erbel, Christian (Author) , Gleißner, Christian A. (Author) , Akhavanpoor, Mohammadreza (Author) , Frankenstein, Lutz (Author) , Darche, Fabrice Fernand (Author) , Schweizer, Patrick Alexander (Author) , Thomas, Dierk (Author) , Ehlermann, Philipp (Author) , Bruckner, Thomas (Author) , Katus, Hugo (Author) , Dösch, Andreas (Author)
Format: Article (Journal)
Language:English
Published: 16 February 2016
In: Drug design, development and therapy
Year: 2016, Volume: 10, Pages: 677-686
ISSN:1177-8881
DOI:10.2147/DDDT.S96126
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.2147/DDDT.S96126
Verlag, lizenzpflichtig, Volltext: https://www.dovepress.com/long-term-use-of-amiodarone-before-heart-transplantation-significantly-peer-reviewed-article-DDDT
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Author Notes:Rasmus Rivinius, Matthias Helmschrott, Arjang Ruhparwar, Bastian Schmack, Christian Erbel, Christian A. Gleissner, Mohammadreza Akhavanpoor, Lutz Frankenstein, Fabrice F. Darche, Patrick A. Schweizer, Dierk Thomas, Philipp Ehlermann, Thomas Bruckner, Hugo A. Katus, Andreas O. Doesch
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Summary:Amiodarone is a frequently used antiarrhythmic drug in patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been controversially discussed, with divergent results regarding morbidity and mortality after heart transplantation (HTX).Aim: The aim of this study was to investigate the effects of long-term use of amiodarone before HTX on early post-transplant atrial fibrillation (AF) and mortality after HTX.
Item Description:Gesehen am 30.04.2020
Physical Description:Online Resource
ISSN:1177-8881
DOI:10.2147/DDDT.S96126