Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation
Amiodarone is a frequently used antiarrhythmic drug in patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been controversially discussed, with divergent results regarding morbidity and mortality after heart transplantation (HTX).Aim: The aim of thi...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 February 2016
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| In: |
Drug design, development and therapy
Year: 2016, Volume: 10, Pages: 677-686 |
| ISSN: | 1177-8881 |
| DOI: | 10.2147/DDDT.S96126 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.2147/DDDT.S96126 Verlag, lizenzpflichtig, Volltext: https://www.dovepress.com/long-term-use-of-amiodarone-before-heart-transplantation-significantly-peer-reviewed-article-DDDT |
| Author Notes: | Rasmus Rivinius, Matthias Helmschrott, Arjang Ruhparwar, Bastian Schmack, Christian Erbel, Christian A. Gleissner, Mohammadreza Akhavanpoor, Lutz Frankenstein, Fabrice F. Darche, Patrick A. Schweizer, Dierk Thomas, Philipp Ehlermann, Thomas Bruckner, Hugo A. Katus, Andreas O. Doesch |
| Summary: | Amiodarone is a frequently used antiarrhythmic drug in patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been controversially discussed, with divergent results regarding morbidity and mortality after heart transplantation (HTX).Aim: The aim of this study was to investigate the effects of long-term use of amiodarone before HTX on early post-transplant atrial fibrillation (AF) and mortality after HTX. |
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| Item Description: | Gesehen am 30.04.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1177-8881 |
| DOI: | 10.2147/DDDT.S96126 |