Resting vagal activity in schizophrenia: meta-analysis of heart rate variability as a potential endophenotype
Background - Cardiac vagal tone, indexed by heart rate variability (HRV), is a proxy - for the functional integrity of feedback mechanisms integrating central - and peripheral physiology. Aims - To quantify differences in HRV in individuals with schizophrenia compared - with healthy controls. Method...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
|
| In: |
The British journal of psychiatry
Year: 2015, Volume: 208, Issue: 1, Pages: 9-16 |
| ISSN: | 1472-1465 |
| DOI: | 10.1192/bjp.bp.114.160762 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1192/bjp.bp.114.160762 Verlag, lizenzpflichtig, Volltext: https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/resting-vagal-activity-in-schizophrenia-metaanalysis-of-heart-rate-variability-as-a-potential-endophenotype/7A76D9F7D23BD889E7CA39A98CE42A66 
|
| Author Notes: | Annika Clamor, Tania M. Lincoln, Julian F. Thayer and Julian Koenig |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1697016375 | ||
| 003 | DE-627 | ||
| 005 | 20220818064528.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200504r20162015xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1192/bjp.bp.114.160762 |2 doi | |
| 035 | |a (DE-627)1697016375 | ||
| 035 | |a (DE-599)KXP1697016375 | ||
| 035 | |a (OCoLC)1341318135 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Clamor, Annika |e VerfasserIn |0 (DE-588)1145070949 |0 (DE-627)1005294909 |0 (DE-576)495610887 |4 aut | |
| 245 | 1 | 0 | |a Resting vagal activity in schizophrenia |b meta-analysis of heart rate variability as a potential endophenotype |c Annika Clamor, Tania M. Lincoln, Julian F. Thayer and Julian Koenig |
| 264 | 1 | |c 2016 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a accepted 19 Feb 2015 | ||
| 500 | |a Gesehen am 04.05.2020 | ||
| 520 | |a Background - Cardiac vagal tone, indexed by heart rate variability (HRV), is a proxy - for the functional integrity of feedback mechanisms integrating central - and peripheral physiology. Aims - To quantify differences in HRV in individuals with schizophrenia compared - with healthy controls. Method - Databases were systematically searched for studies eligible for - inclusion. Random effect meta-analyses of standardised mean differences - were calculated for vagal activity indicated by high-frequency HRV and - the root mean square of successive R-R interval differences (RMSSD). Results - Thirty-four studies were included. Significant main effects were found - for high-frequency HRV (P = 0.0008; Hedges' - g =-0.98, 95% CI −1.56 to −0.41, k = - 29) and RMSSD (P<0.0001; g =-0.91, - 95% CI −1.19 to −0.62, k = 24), indicating lower vagal - activity in individuals with schizophrenia than in healthy controls. - Considerable heterogeneity was evident but effects were robust in - subsequent sensitivity analyses. Conclusions - Given the association between low HRV, threat processing, emotion - regulation and executive functioning, reduced vagal tone may be an - endophenotype for the development of psychotic symptoms. | ||
| 534 | |c 2015 | ||
| 700 | 1 | |a Lincoln, Tania M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Thayer, Julian F. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Koenig, Julian |d 1985- |e VerfasserIn |0 (DE-588)1031388052 |0 (DE-627)736334459 |0 (DE-576)378827227 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The British journal of psychiatry |d Cambridge : Cambridge University Press, 1963 |g 208(2016), 1, Seite 9-16 |h Online-Ressource |w (DE-627)320240754 |w (DE-600)2021500-9 |w (DE-576)09388849X |x 1472-1465 |7 nnas |a Resting vagal activity in schizophrenia meta-analysis of heart rate variability as a potential endophenotype |
| 773 | 1 | 8 | |g volume:208 |g year:2016 |g number:1 |g pages:9-16 |g extent:8 |a Resting vagal activity in schizophrenia meta-analysis of heart rate variability as a potential endophenotype |
| 856 | 4 | 0 | |u https://doi.org/10.1192/bjp.bp.114.160762 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/resting-vagal-activity-in-schizophrenia-metaanalysis-of-heart-rate-variability-as-a-potential-endophenotype/7A76D9F7D23BD889E7CA39A98CE42A66 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200504 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1031388052 |a Koenig, Julian |m 1031388052:Koenig, Julian |d 910000 |d 910600 |e 910000PK1031388052 |e 910600PK1031388052 |k 0/910000/ |k 1/910000/910600/ |p 4 |y j | ||
| 999 | |a KXP-PPN1697016375 |e 3656773505 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Annika Clamor, Tania M. Lincoln, Julian F. Thayer and Julian Koenig"]},"person":[{"family":"Clamor","role":"aut","given":"Annika","display":"Clamor, Annika"},{"family":"Lincoln","role":"aut","given":"Tania M.","display":"Lincoln, Tania M."},{"display":"Thayer, Julian F.","given":"Julian F.","role":"aut","family":"Thayer"},{"given":"Julian","role":"aut","display":"Koenig, Julian","family":"Koenig"}],"recId":"1697016375","origin":[{"dateIssuedDisp":"2016","dateIssuedKey":"2016"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"relHost":[{"part":{"pages":"9-16","extent":"8","issue":"1","volume":"208","year":"2016","text":"208(2016), 1, Seite 9-16"},"language":["eng"],"title":[{"title":"The British journal of psychiatry","subtitle":"BJPsych","title_sort":"British journal of psychiatry"}],"pubHistory":["109.1963 -"],"name":{"displayForm":["publ. by the Royal College of Psychiatrists"]},"note":["Gesehen am 06.06.2018"],"corporate":[{"display":"Royal College of Psychiatrists","role":"isb"}],"id":{"issn":["1472-1465"],"zdb":["2021500-9"],"eki":["320240754"]},"disp":"Resting vagal activity in schizophrenia meta-analysis of heart rate variability as a potential endophenotypeThe British journal of psychiatry","physDesc":[{"extent":"Online-Ressource"}],"titleAlt":[{"title":"BJPsych"},{"title":"BJP"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"320240754","origin":[{"dateIssuedDisp":"1963-","publisher":"Cambridge University Press ; The Royal College of Psychiatrists","dateIssuedKey":"1963","publisherPlace":"Cambridge ; London"}]}],"note":["accepted 19 Feb 2015","Gesehen am 04.05.2020"],"physDesc":[{"extent":"8 S."}],"id":{"doi":["10.1192/bjp.bp.114.160762"],"eki":["1697016375"]},"language":["eng"],"title":[{"subtitle":"meta-analysis of heart rate variability as a potential endophenotype","title":"Resting vagal activity in schizophrenia","title_sort":"Resting vagal activity in schizophrenia"}]} | ||
| SRT | |a CLAMORANNIRESTINGVAG2016 | ||