Immunotherapy of pancreatic cancer - weal and woe

We appreciated reading the commentary “Pancreatic ductal adenocarcinoma—a new hope?” of Irving and Lobo (1) on our recent paper in the British Journal of Cancer (2). Indeed, pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in the world. At present, only multimodal treatment...

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Hauptverfasser: Bazhin, Alexandr V. (VerfasserIn) , Werner, Jens (VerfasserIn) , Karakhanova, Svetlana (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: November 2016
In: Translational cancer research
Year: 2016, Jahrgang: 5, Heft: 6, Pages: S1295-S1296
ISSN:2219-6803
DOI:10.21037/tcr.2016.11.24
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.21037/tcr.2016.11.24
Verlag, lizenzpflichtig, Volltext: http://tcr.amegroups.com/article/view/10450
Volltext
Verfasserangaben:Alexandr V. Bazhin, Jens Werner, Svetlana Karakhanova
Beschreibung
Zusammenfassung:We appreciated reading the commentary “Pancreatic ductal adenocarcinoma—a new hope?” of Irving and Lobo (1) on our recent paper in the British Journal of Cancer (2). Indeed, pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in the world. At present, only multimodal treatment including surgical resection can prolong survival of patients with this disease (3). Therefore, new therapeutic approaches against PDAC are urgently needed. One new option is to apply immunotherapy for these patients. Immunotherapy possesses a bright spectrum of approaches: (I) passive immunotherapy includes a treatment of patients with monoclonal antibodies (specific immunotherapy) or checkpoint inhibitors (non-specific immunotherapy); (II) cancer vaccines and cellular therapy belong to the active immunotherapy as well as interferon treatment (non-specific immunotherapy).
Beschreibung:Gesehen am 04.05.2020
Beschreibung:Online Resource
ISSN:2219-6803
DOI:10.21037/tcr.2016.11.24