Imagining the future of bioimage analysis

Modern biological research increasingly relies on image data as a primary source of information in unraveling the cellular and molecular mechanisms of life. The quantity and complexity of the data generated by state-of-the-art microscopes preclude visual or manual analysis and require advanced compu...

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Bibliographic Details
Main Authors: Meijering, Erik (Author) , Carpenter, Anne E. (Author) , Peng, Hanchuan (Author) , Hamprecht, Fred (Author) , Olivo-Marin, Jean-Christophe (Author)
Format: Article (Journal)
Language:English
Published: 7 December 2016
In: Nature biotechnology
Year: 2016, Volume: 34, Issue: 12, Pages: 1250-1255
ISSN:1546-1696
DOI:10.1038/nbt.3722
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nbt.3722
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nbt.3722
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Author Notes:Erik Meijering, Anne E Carpenter, Hanchuan Peng, Fred A Hamprecht & Jean-Christophe Olivo-Marin
Description
Summary:Modern biological research increasingly relies on image data as a primary source of information in unraveling the cellular and molecular mechanisms of life. The quantity and complexity of the data generated by state-of-the-art microscopes preclude visual or manual analysis and require advanced computational methods to fully explore the wealth of information. In addition to making bioimage analysis more efficient, objective, and reproducible, the use of computers improves the accuracy and sensitivity of the analyses and helps to reveal subtleties that may be unnoticeable to the human eye. Many methods and software tools have already been developed to this end, but there is still a long way to go before biologists can blindly trust automated measurements. Here, we summarize the current state of the art in bioimage analysis and provide a perspective on likely future developments.
Item Description:Gesehen am 05.05.2020
Physical Description:Online Resource
ISSN:1546-1696
DOI:10.1038/nbt.3722