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Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage

In the adult brain, vascular endothelial growth factor D (VEGFD) is required for structural integrity of dendrites and cognitive abilities. Alterations of dendritic architectures are hallmarks of many neurologic disorders, including stroke-induced damage caused by toxic extrasynaptic NMDA receptor (...

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Main Authors: Mauceri, Daniela (Author) , Buchthal, Bettina (Author) , Hemstedt, Thekla Joana (Author) , Weiss, Ursula (Author) , Klein, Christian D. (Author) , Bading, Hilmar (Author)
Format: Article (Journal)
Language:English
Published: March 30, 2020
In: Proceedings of the National Academy of Sciences of the United States of America
Year: 2020, Volume: 117, Issue: 15, Pages: 8616-8623
ISSN:1091-6490
DOI:10.1073/pnas.2001563117
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1073/pnas.2001563117
Verlag, lizenzpflichtig, Volltext: https://www.pnas.org/content/117/15/8616
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Author Notes:Daniela Mauceri, Bettina Buchthal, Thekla J. Hemstedt, Ursula Weiss, Christian D. Klein, and Hilmar Bading

MARC

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