Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling
Vascular smooth muscle (VSM) expresses calcium/calmodulin-dependent protein kinase II (CaMKII)-δ and -γ isoforms. CaMKIIδ promotes VSM proliferation and vascular remodeling. We tested CaMKIIγ function in vascular remodeling after injury.
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| In: |
The FASEB journal
Year: 2015, Jahrgang: 30, Heft: 3, Pages: 1051-1064 |
| ISSN: | 1530-6860 |
| DOI: | 10.1096/fj.15-279158 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1096/fj.15-279158 Verlag, lizenzpflichtig, Volltext: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.15-279158 |
| Verfasserangaben: | Fatima Z. Saddouk, Li-Yan Sun, Yong Feng Liu, Miao Jiang, Diane V. Singer, Johannes Backs, Dee Van Riper, Roman Ginnan, John J. Schwarz, and Harold A. Singer |
| Zusammenfassung: | Vascular smooth muscle (VSM) expresses calcium/calmodulin-dependent protein kinase II (CaMKII)-δ and -γ isoforms. CaMKIIδ promotes VSM proliferation and vascular remodeling. We tested CaMKIIγ function in vascular remodeling after injury. |
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| Beschreibung: | First published: 13 November 2015 Gesehen am 07.05.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1530-6860 |
| DOI: | 10.1096/fj.15-279158 |