Prevalence of contact allergy to p-phenylenediamine in the European general population
Population-based studies on contact allergy to <i>p</i>-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were inte...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| In: |
The journal of investigative dermatology
Year: 2015, Jahrgang: 136, Heft: 2, Pages: 409-415 |
| ISSN: | 1523-1747 |
| DOI: | 10.1016/j.jid.2015.10.064 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jid.2015.10.064 Verlag, lizenzpflichtig, Volltext: https://www.jidonline.org/article/S0022-202X(15)00065-2/abstract 
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| Verfasserangaben: | Thomas L. Diepgen, Luigi Naldi, Magnus Bruze, Simone Cazzaniga, Marie-Louise Schuttelaar, Peter Elsner, Margarida Goncalo, Robert Ofenloch and Åke Svensson |
MARC
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| 520 | |a Population-based studies on contact allergy to <i>p</i>-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a random sample (n = 2,739) was patch tested to PPD. Overall, 5,286 individuals (50.9%) reported having used hair colorants at least once in their lifetime (78% female, 20% male), and 35% had used hair colorants during the last 12 months. Hair colorant avoidance because of any skin problem during the lifetime was reported by 6%. Black henna tattoos had been used by 5.5% during their lifetime. The prevalence of PPD contact allergy was 0.8% (95% confidence interval 0.6-1.0%), with no statistically significant association with gender or hair dye use. The prevalence of PPD in black henna tattoo users was 3.2% versus 0.6% in nonusers (<i>P</i> < 0.001). A clinically relevant positive patch test reaction to PPD related to hair coloring products was found in 0.1% (95% confidence interval 0.0-0.2%). A significant association with PPD contact allergy was observed for subjects who had black henna tattoos in their lifetime, with an age- and gender-adjusted odds ratio of 9.33 (95% confidence interval 3.45-25.26, <i>P</i> < 0.001). Black henna tattoos are an important risk factor for PPD contact allergy. | ||
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