Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit

The ribosome-assembly factor Mrt4 prevents untimely recruitment of the RNA-export receptor Mex67-Mtr2 to the nascent 60S ribosomal subunit, thereby ensuring appropriately timed nuclear export.

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Bibliographic Details
Main Authors: Sarkar, Anshuk (Author) , Pech, Markus (Author) , Thoms, Matthias (Author) , Beckmann, Roland (Author) , Hurt, Ed (Author)
Format: Article (Journal)
Language:English
Published: 24 October 2016
In: Nature structural & molecular biology
Year: 2016, Volume: 23, Issue: 12, Pages: 1074-1082
ISSN:1545-9985
DOI:10.1038/nsmb.3312
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1038/nsmb.3312
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nsmb.3312
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Author Notes:Anshuk Sarkar, Markus Pech, Matthias Thoms, Roland Beckmann & Ed Hurt
Description
Summary:The ribosome-assembly factor Mrt4 prevents untimely recruitment of the RNA-export receptor Mex67-Mtr2 to the nascent 60S ribosomal subunit, thereby ensuring appropriately timed nuclear export.
Item Description:Gesehen am 08.05.2020
Physical Description:Online Resource
ISSN:1545-9985
DOI:10.1038/nsmb.3312