A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors
This study presents OncoTreat, a framework for the prioritization of compounds targeting mechanistic tumor dependencies in individual patients.
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
18 June 2018
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| In: |
Nature genetics
Year: 2018, Volume: 50, Issue: 7, Pages: 979-989 |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/s41588-018-0138-4 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41588-018-0138-4 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41588-018-0138-4 
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| Author Notes: | Mariano J. Alvarez, Prem S. Subramaniam, Laura H. Tang, Adina Grunn, Mahalaxmi Aburi, Gabrielle Rieckhof, Elena V. Komissarova, Elizabeth A. Hagan, Lisa Bodei, Paul A. Clemons, Filemon S. Dela Cruz, Deepti Dhall, Daniel Diolaiti, Douglas A. Fraker, Afshin Ghavami, Daniel Kaemmerer, Charles Karan, Mark Kidd, Kyoung M. Kim, Hee C. Kim, Lakshmi P. Kunju, Ülo Langel, Zhong Li, Jeeyun Lee, Hai Li, Virginia LiVolsi, Roswitha Pfragner, Allison R. Rainey, Ronald B. Realubit, Helen Remotti, Jakob Regberg, Robert Roses, Anil Rustgi, Antonia R. Sepulveda, Stefano Serra, Chanjuan Shi, Xiaopu Yuan, Massimo Barberis, Roberto Bergamaschi, Arul M. Chinnaiyan, Tony Detre, Shereen Ezzat, Andrea Frilling, Merten Hommann, Dirk Jaeger, Michelle K. Kim, Beatrice S. Knudsen, Andrew L. Kung, Emer Leahy, David C. Metz, Jeffrey W. Milsom, Young S. Park, Diane Reidy-Lagunes, Stuart Schreiber, Kay Washington, Bertram Wiedenmann, Irvin Modlin and Andrea Califano |
| Summary: | This study presents OncoTreat, a framework for the prioritization of compounds targeting mechanistic tumor dependencies in individual patients. |
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| Item Description: | Gesehen am 11.05.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/s41588-018-0138-4 |