Alternative modes of client binding enable functional plasticity of Hsp70: letter

Hsp70 binds unfolded protein segments in its groove, but can also bind and stabilize folded protein structures, owing to its moveable lid, with ATP hydrolysis and co-chaperones allowing control of these contrasting effects.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mashaghi Tabari, Alireza (VerfasserIn) , Bezrukavnikov, Sergey (VerfasserIn) , Minde, David P. (VerfasserIn) , Wentink, Anne (VerfasserIn) , Kityk, Roman (VerfasserIn) , Zachmann-Brand, Beate (VerfasserIn) , Mayer, Matthias P. (VerfasserIn) , Kramer, Günter (VerfasserIn) , Bukau, Bernd (VerfasserIn) , Tans, Sander J. (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 26 October 2016
In: Nature
Year: 2016, Jahrgang: 539, Heft: 7629, Pages: 448-451
ISSN:1476-4687
DOI:10.1038/nature20137
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature20137
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature20137
Volltext
Verfasserangaben:Alireza Mashaghi, Sergey Bezrukavnikov, David P. Minde, Anne S. Wentink, Roman Kityk, Beate Zachmann-Brand, Matthias P. Mayer, Günter Kramer, Bernd Bukau & Sander J. Tans

MARC

LEADER 00000caa a2200000 c 4500
001 1698042981
003 DE-627
005 20220818082729.0
007 cr uuu---uuuuu
008 200512s2016 xx |||||o 00| ||eng c
024 7 |a 10.1038/nature20137  |2 doi 
035 |a (DE-627)1698042981 
035 |a (DE-599)KXP1698042981 
035 |a (OCoLC)1341323405 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 32  |2 sdnb 
100 1 |a Mashaghi Tabari, Alireza  |e VerfasserIn  |0 (DE-588)1209980754  |0 (DE-627)1698055277  |4 aut 
245 1 0 |a Alternative modes of client binding enable functional plasticity of Hsp70  |b letter  |c Alireza Mashaghi, Sergey Bezrukavnikov, David P. Minde, Anne S. Wentink, Roman Kityk, Beate Zachmann-Brand, Matthias P. Mayer, Günter Kramer, Bernd Bukau & Sander J. Tans 
264 1 |c 26 October 2016 
300 |a 4 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 12.05.2020 
520 |a Hsp70 binds unfolded protein segments in its groove, but can also bind and stabilize folded protein structures, owing to its moveable lid, with ATP hydrolysis and co-chaperones allowing control of these contrasting effects. 
700 1 |a Bezrukavnikov, Sergey  |e VerfasserIn  |0 (DE-588)120408873X  |0 (DE-627)1689221135  |4 aut 
700 1 |a Minde, David P.  |e VerfasserIn  |4 aut 
700 1 |a Wentink, Anne  |e VerfasserIn  |0 (DE-588)1192322258  |0 (DE-627)1670641759  |4 aut 
700 1 |a Kityk, Roman  |e VerfasserIn  |0 (DE-588)108303863X  |0 (DE-627)84784952X  |0 (DE-576)455628645  |4 aut 
700 1 |a Zachmann-Brand, Beate  |e VerfasserIn  |0 (DE-588)1098172795  |0 (DE-627)857465244  |0 (DE-576)469003944  |4 aut 
700 1 |a Mayer, Matthias P.  |d 1960-  |e VerfasserIn  |0 (DE-588)1060239752  |0 (DE-627)799340510  |0 (DE-576)167058827  |4 aut 
700 1 |a Kramer, Günter  |e VerfasserIn  |0 (DE-588)1060239582  |0 (DE-627)799340294  |0 (DE-576)416341136  |4 aut 
700 1 |a Bukau, Bernd  |d 1954-  |e VerfasserIn  |0 (DE-588)143209019  |0 (DE-627)643892575  |0 (DE-576)335649270  |4 aut 
700 1 |a Tans, Sander J.  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Nature  |d London [u.a.] : Nature Publ. Group, 1869  |g 539(2016), 7629, Seite 448-451  |h Online-Ressource  |w (DE-627)240151402  |w (DE-600)1413423-8  |w (DE-576)079718426  |x 1476-4687  |7 nnas  |a Alternative modes of client binding enable functional plasticity of Hsp70 letter 
773 1 8 |g volume:539  |g year:2016  |g number:7629  |g pages:448-451  |g extent:4  |a Alternative modes of client binding enable functional plasticity of Hsp70 letter 
856 4 0 |u https://doi.org/10.1038/nature20137  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.nature.com/articles/nature20137  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20200512 
993 |a Editorial 
994 |a 2016 
998 |g 143209019  |a Bukau, Bernd  |m 143209019:Bukau, Bernd  |d 700000  |d 706000  |e 700000PB143209019  |e 706000PB143209019  |k 0/700000/  |k 1/700000/706000/  |p 9 
998 |g 1060239582  |a Kramer, Günter  |m 1060239582:Kramer, Günter  |d 700000  |d 706000  |e 700000PK1060239582  |e 706000PK1060239582  |k 0/700000/  |k 1/700000/706000/  |p 8 
998 |g 1060239752  |a Mayer, Matthias P.  |m 1060239752:Mayer, Matthias P.  |d 700000  |d 706000  |e 700000PM1060239752  |e 706000PM1060239752  |k 0/700000/  |k 1/700000/706000/  |p 7 
998 |g 1098172795  |a Zachmann-Brand, Beate  |m 1098172795:Zachmann-Brand, Beate  |d 700000  |d 706000  |e 700000PZ1098172795  |e 706000PZ1098172795  |k 0/700000/  |k 1/700000/706000/  |p 6 
998 |g 108303863X  |a Kityk, Roman  |m 108303863X:Kityk, Roman  |d 700000  |d 706000  |e 700000PK108303863X  |e 706000PK108303863X  |k 0/700000/  |k 1/700000/706000/  |p 5 
998 |g 1192322258  |a Wentink, Anne  |m 1192322258:Wentink, Anne  |d 700000  |d 706000  |e 700000PW1192322258  |e 706000PW1192322258  |k 0/700000/  |k 1/700000/706000/  |p 4 
999 |a KXP-PPN1698042981  |e 3664911903 
BIB |a Y 
SER |a newspaper 
JSO |a {"name":{"displayForm":["Alireza Mashaghi, Sergey Bezrukavnikov, David P. Minde, Anne S. Wentink, Roman Kityk, Beate Zachmann-Brand, Matthias P. Mayer, Günter Kramer, Bernd Bukau & Sander J. Tans"]},"origin":[{"dateIssuedDisp":"26 October 2016","dateIssuedKey":"2016"}],"type":{"bibl":"article-newspaper","media":"Online-Ressource"},"recId":"1698042981","id":{"eki":["1698042981"],"doi":["10.1038/nature20137"]},"person":[{"role":"aut","family":"Mashaghi Tabari","display":"Mashaghi Tabari, Alireza","given":"Alireza"},{"display":"Bezrukavnikov, Sergey","role":"aut","family":"Bezrukavnikov","given":"Sergey"},{"display":"Minde, David P.","family":"Minde","role":"aut","given":"David P."},{"display":"Wentink, Anne","role":"aut","family":"Wentink","given":"Anne"},{"display":"Kityk, Roman","role":"aut","family":"Kityk","given":"Roman"},{"given":"Beate","display":"Zachmann-Brand, Beate","role":"aut","family":"Zachmann-Brand"},{"family":"Mayer","role":"aut","display":"Mayer, Matthias P.","given":"Matthias P."},{"given":"Günter","role":"aut","family":"Kramer","display":"Kramer, Günter"},{"display":"Bukau, Bernd","role":"aut","family":"Bukau","given":"Bernd"},{"display":"Tans, Sander J.","family":"Tans","role":"aut","given":"Sander J."}],"language":["eng"],"note":["Gesehen am 12.05.2020"],"title":[{"title":"Alternative modes of client binding enable functional plasticity of Hsp70","subtitle":"letter","title_sort":"Alternative modes of client binding enable functional plasticity of Hsp70"}],"physDesc":[{"extent":"4 S."}],"relHost":[{"type":{"media":"Online-Ressource","bibl":"newspaper"},"recId":"240151402","id":{"issn":["1476-4687"],"zdb":["1413423-8"],"eki":["240151402"]},"origin":[{"publisher":"Nature Publ. Group ; Macmillan","dateIssuedDisp":"1869-","publisherPlace":"London [u.a.] ; London","dateIssuedKey":"1869"}],"disp":"Alternative modes of client binding enable functional plasticity of Hsp70 letterNature","language":["eng"],"pubHistory":["1.1869/70 - ; auch mit durchgehender Nr.-Zählung"],"note":["Gesehen am 19.02.2019"],"titleAlt":[{"title":"Nature <London>"},{"title":"Nature"}],"part":{"issue":"7629","pages":"448-451","year":"2016","extent":"4","volume":"539","text":"539(2016), 7629, Seite 448-451"},"title":[{"title_sort":"Nature","subtitle":"international weekly journal of science","title":"Nature"}],"physDesc":[{"extent":"Online-Ressource"}]}]} 
SRT |a MASHAGHITAALTERNATIV2620