Selective binding and lateral clustering of α5β1 and αvβ3 integrins: unraveling the spatial requirements for cell spreading and focal adhesion assembly
Coordination of the specific functions of α5β1 and αvβ3 integrins is crucial for the precise regulation of cell adhesion, spreading and migration, yet the contribution of differential integrin-specific crosstalk to these processes remains unclear. To determine the specific functions of αvβ3 and α5β1...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 Apr 2016
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| In: |
Cell adhesion & migration
Year: 2016, Jahrgang: 10, Heft: 5, Pages: 505-515 |
| ISSN: | 1933-6926 |
| DOI: | 10.1080/19336918.2016.1163453 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1080/19336918.2016.1163453 Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/full/10.1080/19336918.2016.1163453 
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| Verfasserangaben: | Viktoria Schaufler, Helmi Czichos-Medda, Vera Hirschfeld-Warnecken, Stefanie Neubauer, Florian Rechenmacher, Rebecca Medda, Horst Kessler, Benjamin Geiger, Joachim P. Spatz & E. Ada Cavalcanti-Adam |
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| 520 | |a Coordination of the specific functions of α5β1 and αvβ3 integrins is crucial for the precise regulation of cell adhesion, spreading and migration, yet the contribution of differential integrin-specific crosstalk to these processes remains unclear. To determine the specific functions of αvβ3 and α5β1 integrins, we used nanoarrays of gold particles presenting immobilized, integrin-selective peptidomimetic ligands. | ||
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