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Global profiling of SRP interaction with nascent polypeptides

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Here, the selection of substrates by the protein-RNA complex known as the signal recognition particle (SRP) is investigated in the bacterium Escherichia coli, revealing that the SRP has a strong preference for hydrophobic transmembrane domains of inner membrane proteins.

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Bibliographische Detailangaben
Hauptverfasser: Schibich, Daniela (VerfasserIn) , Gloge, Felix (VerfasserIn) , Pöhner, Ina (VerfasserIn) , Björkholm, Patrik (VerfasserIn) , Wade, Rebecca C. (VerfasserIn) , Heijne, Gunnar von (VerfasserIn) , Bukau, Bernd (VerfasserIn) , Kramer, Günter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 3 August 2016
In: Nature
Year: 2016, Jahrgang: 536, Heft: 7615, Pages: 219-223
ISSN:1476-4687
DOI:10.1038/nature19070
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature19070
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature19070
Volltext
Verfasserangaben:Daniela Schibich, Felix Gloge, Ina Pöhner, Patrik Björkholm, Rebecca C. Wade, Gunnar von Heijne, Bernd Bukau & Günter Kramer

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