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Contemporary review of the organ care system in lung transplantation: potential advantages of a portable ex-vivo lung perfusion system

Lung transplantation remains the definite treatment for various end-stage lung diseases. Cold flush perfusion, the standard method for organ procurement has severe limitations. Organ Care System (OCS; TransMedics, Inc., Andover, USA) is an approved method to preserve hearts for transplantation that...

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Main Authors: Schmack, Bastian (Author) , Weymann, Alexander (Author) , Mohite, Prashant (Author) , Saez, Diana Garcia (Author) , Zych, Bartlomiej (Author) , Sabashnikov, Anton (Author) , Zeriouh, Mohamed (Author) , Schamroth, Joel (Author) , Koch, Achim (Author) , Soresi, Simona (Author) , Ananiadou, Olga (Author) , Robertis, Fabio De (Author) , Karck, Matthias (Author) , Simon, André R. (Author) , Popov, Aron Frederik (Author)
Format: Article (Journal)
Language:English
Published: 20 Oct 2016
In: Expert review of medical devices
Year: 2016, Volume: 13, Issue: 11, Pages: 1035-1041
ISSN:1745-2422
DOI:10.1080/17434440.2016.1243464
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1080/17434440.2016.1243464
Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/full/10.1080/17434440.2016.1243464
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Author Notes:Bastian Schmack, Alexander Weymann, Prashant Mohite, Diana Garcia Saez, Bartlomiej Zych, Anton Sabashnikov, Mohamed Zeriouh, Joel Schamroth, Achim Koch, Simona Soresi, Olga Ananiadou, Fabio De Robertis, Matthias Karck, Andre Ruediger Simon, Aron Frederik Popov
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Summary:Lung transplantation remains the definite treatment for various end-stage lung diseases. Cold flush perfusion, the standard method for organ procurement has severe limitations. Organ Care System (OCS; TransMedics, Inc., Andover, USA) is an approved method to preserve hearts for transplantation that allows for greatly reduced cold ischemic time. Consequently, the use of an adapted OCS lung as a portable full ex-vivo lung perfusion system in lung transplantation is currently under close evaluation. Areas covered: The aim of this article is to review the advantages and the role of the OCS in the field of lung transplantation by reviewing the latest literature and evaluating this novel procurement technique in the context of conventional methods like cold flush and regular ex-vivo lung perfusion.
Item Description:Gesehen am 15.05.2020
Physical Description:Online Resource
ISSN:1745-2422
DOI:10.1080/17434440.2016.1243464

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