Cancer-related fatigue shows a stable association with diurnal cortisol dysregulation in breast cancer patients

Fatigue is a major burden for breast cancer patients undergoing adjuvant therapy. Yet, its pathophysiology is still not well understood. Hypothesized mechanisms include dysregulations in the hypothalamic-pituitary-adrenal (HPA) axis, which may be reflected in alterations in the diurnal cortisol patt...

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Bibliographic Details
Main Authors: Schmidt, Martina (Author) , Semik, Johanna (Author) , Habermann, Nina (Author) , Wiskemann, Joachim (Author) , Ulrich, Cornelia (Author) , Steindorf, Karen (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: Brain, behavior and immunity
Year: 2015, Volume: 52, Pages: 98-105
ISSN:1090-2139
DOI:10.1016/j.bbi.2015.10.005
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.bbi.2015.10.005
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0889159115300301
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Author Notes:Martina E. Schmidt, Johanna Semik, Nina Habermann, Joachim Wiskemann, Cornelia M. Ulrich, Karen Steindorf
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Summary:Fatigue is a major burden for breast cancer patients undergoing adjuvant therapy. Yet, its pathophysiology is still not well understood. Hypothesized mechanisms include dysregulations in the hypothalamic-pituitary-adrenal (HPA) axis, which may be reflected in alterations in the diurnal cortisol patterns. However, studies on the association between cortisol and fatigue during adjuvant cancer therapy are rare.
Item Description:Available online 9 October 2015
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Physical Description:Online Resource
ISSN:1090-2139
DOI:10.1016/j.bbi.2015.10.005