Distinct types of feeding related neurons in mouse hypothalamus
The last two decades of research provided evidence for a substantial heterogeneity among feeding-related neurons (FRNs) in the hypothalamus. However, it remains unclear how FRNs differ in their firing patterns during food intake. Here, we investigated the relationship between the activity of neurons...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
[18 May 2016]
|
| In: |
Frontiers in behavioral neuroscience
Year: 2016, Jahrgang: 10 |
| ISSN: | 1662-5153 |
| DOI: | 10.3389/fnbeh.2016.00091 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3389/fnbeh.2016.00091 Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fnbeh.2016.00091/full 
|
| Verfasserangaben: | Yan Tang, Diego Benusiglio, Valery Grinevich and Longnian Lin |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1698606591 | ||
| 003 | DE-627 | ||
| 005 | 20220818092712.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200520s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3389/fnbeh.2016.00091 |2 doi | |
| 035 | |a (DE-627)1698606591 | ||
| 035 | |a (DE-599)KXP1698606591 | ||
| 035 | |a (OCoLC)1341325907 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Tang, Yan |e VerfasserIn |0 (DE-588)1192486919 |0 (DE-627)1671039084 |4 aut | |
| 245 | 1 | 0 | |a Distinct types of feeding related neurons in mouse hypothalamus |c Yan Tang, Diego Benusiglio, Valery Grinevich and Longnian Lin |
| 264 | 1 | |c [18 May 2016] | |
| 300 | |b Diagramme | ||
| 300 | |a ? | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 20.05.2020 | ||
| 520 | |a The last two decades of research provided evidence for a substantial heterogeneity among feeding-related neurons (FRNs) in the hypothalamus. However, it remains unclear how FRNs differ in their firing patterns during food intake. Here, we investigated the relationship between the activity of neurons in mouse hypothalamus and their feeding behavior. Using tetrode-based in vivo recording technique, we identified various firing patterns of hypothalamic FRNs, which, after the initiation of food intake, can be sorted into four types: sharp increase (type I), slow increase (type II), sharp decrease (type III) and sustained decrease (type IV) of firing rates. The feeding-related firing response of FRNs was rigidly related to the duration of food intake and, to a less extent, associated with the type of food. The majority of these FRNs responded to glucose and leptin and exhibited electrophysiological characteristics of putative GABAergic neurons. In conclusion, our study demonstrated the diversity of neurons in the complex hypothalamic network coordinating food intake. | ||
| 650 | 4 | |a Feeding Behavior | |
| 650 | 4 | |a feeding-related neurons | |
| 650 | 4 | |a firing patterns | |
| 650 | 4 | |a food intake | |
| 650 | 4 | |a Hypothalamus | |
| 650 | 4 | |a in vivo multi-channel recording | |
| 700 | 1 | |a Benusiglio, Diego |e VerfasserIn |0 (DE-588)1192487176 |0 (DE-627)1671041038 |4 aut | |
| 700 | 1 | |a Grinevich, Valéry |e VerfasserIn |0 (DE-588)1158696574 |0 (DE-627)1020774606 |0 (DE-576)504314289 |4 aut | |
| 700 | 1 | |a Lin, Longnian |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Frontiers in behavioral neuroscience |d Lausanne : Frontiers Research Foundation, 2007 |g 10(2016) |h Online-Ressource |w (DE-627)579826392 |w (DE-600)2452960-6 |w (DE-576)286502224 |x 1662-5153 |7 nnas |a Distinct types of feeding related neurons in mouse hypothalamus |
| 773 | 1 | 8 | |g volume:10 |g year:2016 |g extent:? |a Distinct types of feeding related neurons in mouse hypothalamus |
| 856 | 4 | 0 | |u https://doi.org/10.3389/fnbeh.2016.00091 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.frontiersin.org/articles/10.3389/fnbeh.2016.00091/full |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200520 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1158696574 |a Grinevich, Valéry |m 1158696574:Grinevich, Valéry |d 140000 |d 700000 |d 718000 |e 140000PG1158696574 |e 700000PG1158696574 |e 718000PG1158696574 |k 0/140000/ |k 0/700000/ |k 1/700000/718000/ |p 3 | ||
| 999 | |a KXP-PPN1698606591 |e 3668766045 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 20.05.2020"],"recId":"1698606591","physDesc":[{"extent":"? S.","noteIll":"Diagramme"}],"name":{"displayForm":["Yan Tang, Diego Benusiglio, Valery Grinevich and Longnian Lin"]},"id":{"eki":["1698606591"],"doi":["10.3389/fnbeh.2016.00091"]},"origin":[{"dateIssuedDisp":"[18 May 2016]","dateIssuedKey":"2016"}],"relHost":[{"id":{"issn":["1662-5153"],"eki":["579826392"],"zdb":["2452960-6"]},"pubHistory":["2007 -"],"type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"579826392","part":{"volume":"10","year":"2016","extent":"?","text":"10(2016)"},"note":["Gesehen am 05.10.20"],"origin":[{"dateIssuedDisp":"2007-","publisher":"Frontiers Research Foundation","publisherPlace":"Lausanne","dateIssuedKey":"2007"}],"name":{"displayForm":["Frontiers Research Foundation"]},"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"disp":"Distinct types of feeding related neurons in mouse hypothalamusFrontiers in behavioral neuroscience","title":[{"title_sort":"Frontiers in behavioral neuroscience","title":"Frontiers in behavioral neuroscience"}]}],"person":[{"family":"Tang","display":"Tang, Yan","given":"Yan","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Benusiglio","given":"Diego","roleDisplay":"VerfasserIn","role":"aut","display":"Benusiglio, Diego"},{"family":"Grinevich","display":"Grinevich, Valéry","given":"Valéry","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Lin","roleDisplay":"VerfasserIn","role":"aut","given":"Longnian","display":"Lin, Longnian"}],"language":["eng"],"title":[{"title":"Distinct types of feeding related neurons in mouse hypothalamus","title_sort":"Distinct types of feeding related neurons in mouse hypothalamus"}]} | ||
| SRT | |a TANGYANBENDISTINCTTY1820 | ||