Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle

Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchica...

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Bibliographic Details
Main Authors: Schröder, Hannes (Author) , Komljenovic, Dorde (Author) , Hecker, Markus (Author) , Korff, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: The FASEB journal
Year: 2015, Volume: 30, Issue: 2, Pages: 923-932
ISSN:1530-6860
DOI:10.1096/fj.15-279240
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1096/fj.15-279240
Verlag, lizenzpflichtig, Volltext: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.15-279240
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Author Notes:Hannes Schröder, Dorde Komljenovic, Markus Hecker, and Thomas Korff
Description
Summary:Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchically organized vasculature of the mouse auricle.
Item Description:First published: 06 November 2015
Gesehen am 22.05.2020
Physical Description:Online Resource
ISSN:1530-6860
DOI:10.1096/fj.15-279240