Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle

Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchica...

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Hauptverfasser: Schröder, Hannes (VerfasserIn) , Komljenovic, Dorde (VerfasserIn) , Hecker, Markus (VerfasserIn) , Korff, Thomas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2016
In: The FASEB journal
Year: 2015, Jahrgang: 30, Heft: 2, Pages: 923-932
ISSN:1530-6860
DOI:10.1096/fj.15-279240
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1096/fj.15-279240
Verlag, lizenzpflichtig, Volltext: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.15-279240
Volltext
Verfasserangaben:Hannes Schröder, Dorde Komljenovic, Markus Hecker, and Thomas Korff
Beschreibung
Zusammenfassung:Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchically organized vasculature of the mouse auricle.
Beschreibung:First published: 06 November 2015
Gesehen am 22.05.2020
Beschreibung:Online Resource
ISSN:1530-6860
DOI:10.1096/fj.15-279240