Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle
Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchica...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| In: |
The FASEB journal
Year: 2015, Jahrgang: 30, Heft: 2, Pages: 923-932 |
| ISSN: | 1530-6860 |
| DOI: | 10.1096/fj.15-279240 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1096/fj.15-279240 Verlag, lizenzpflichtig, Volltext: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.15-279240 |
| Verfasserangaben: | Hannes Schröder, Dorde Komljenovic, Markus Hecker, and Thomas Korff |
| Zusammenfassung: | Subcutaneously growing tumors are widely utilized to study tumor angiogenesis and the efficacy of antiangiogenic therapies in mice. To additionally assess functional and morphologic alterations of the vasculature in the periphery of a growing tumor, we exploited the easily accessible and hierarchically organized vasculature of the mouse auricle. |
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| Beschreibung: | First published: 06 November 2015 Gesehen am 22.05.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1530-6860 |
| DOI: | 10.1096/fj.15-279240 |