High-mobility group AT-hook protein 2 expression and its prognostic significance in MGMT methylated and unmethylated glioblastoma

High-mobility group AT-hook protein 2 (HMGA 2) is a transcription factor associated with malignancy and poor prognosis in a variety of human cancers. We correlated HMGA 2 expression with clinical parameters, survival, and O-6-methylguanine-DNA methyltransferase methylation status (MGMT) in glioblast...

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Main Authors: Schwarm, Frank (Author) , Uhle, Florian (Author) , Schänzer, Anne (Author) , Acker, Till (Author) , Stein, Marco (Author) , Reinges, Marcus H. T. (Author) , Weischer, Cornelia (Author) , Weigand, Markus A. (Author) , Uhl, Eberhard (Author) , Kolodziej, Malgorzata A. (Author)
Format: Article (Journal)
Language:English
Published: February 17, 2016
In: International journal of oncology
Year: 2016, Volume: 48, Issue: 4, Pages: 1485-1492
ISSN:1791-2423
DOI:10.3892/ijo.2016.3397
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3892/ijo.2016.3397
Verlag, lizenzpflichtig, Volltext: http://www.spandidos-publications.com/10.3892/ijo.2016.3397/abstract
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Author Notes:Frank P. Schwarm, Florian Uhle, Anne Schänzer, Till Acker, Marco Stein, Marcus H.T. Reinges, Cornelia Weischer, Marcus A. Weigand, Eberhard Uhl and Malgorzata A. Kolodziej
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Summary:High-mobility group AT-hook protein 2 (HMGA 2) is a transcription factor associated with malignancy and poor prognosis in a variety of human cancers. We correlated HMGA 2 expression with clinical parameters, survival, and O-6-methylguanine-DNA methyltransferase methylation status (MGMT) in glioblastoma patients.
Item Description:Gesehen am 26.05.2020
Physical Description:Online Resource
ISSN:1791-2423
DOI:10.3892/ijo.2016.3397