High-mobility group AT-hook protein 2 expression and its prognostic significance in MGMT methylated and unmethylated glioblastoma
High-mobility group AT-hook protein 2 (HMGA 2) is a transcription factor associated with malignancy and poor prognosis in a variety of human cancers. We correlated HMGA 2 expression with clinical parameters, survival, and O-6-methylguanine-DNA methyltransferase methylation status (MGMT) in glioblast...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 17, 2016
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| In: |
International journal of oncology
Year: 2016, Volume: 48, Issue: 4, Pages: 1485-1492 |
| ISSN: | 1791-2423 |
| DOI: | 10.3892/ijo.2016.3397 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3892/ijo.2016.3397 Verlag, lizenzpflichtig, Volltext: http://www.spandidos-publications.com/10.3892/ijo.2016.3397/abstract |
| Author Notes: | Frank P. Schwarm, Florian Uhle, Anne Schänzer, Till Acker, Marco Stein, Marcus H.T. Reinges, Cornelia Weischer, Marcus A. Weigand, Eberhard Uhl and Malgorzata A. Kolodziej |
| Summary: | High-mobility group AT-hook protein 2 (HMGA 2) is a transcription factor associated with malignancy and poor prognosis in a variety of human cancers. We correlated HMGA 2 expression with clinical parameters, survival, and O-6-methylguanine-DNA methyltransferase methylation status (MGMT) in glioblastoma patients. |
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| Item Description: | Gesehen am 26.05.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1791-2423 |
| DOI: | 10.3892/ijo.2016.3397 |