Concomitant immune-related events in Wilson disease: implications for monitoring chelator therapy
Current guidelines favor the use of chelating agents (d-penicillamine, trientine) in first line therapy of symptomatic Wilson disease patients. Development of chelator induced immunological adverse events are a concern especially under d-penicillamine therapy. This study assessed the prevalence of c...
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| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| In: |
Journal of inherited metabolic disease
Year: 2015, Jahrgang: 39, Heft: 1, Pages: 125-130 |
| ISSN: | 1573-2665 |
| DOI: | 10.1007/s10545-015-9866-0 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10545-015-9866-0 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1007/s10545-015-9866-0 
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| Verfasserangaben: | Jessica Seessle, Daniel Nils Gotthardt, Mark Schäfer, Annina Gohdes, Jan Pfeiffenberger, Peter Ferenci, Wolfgang Stremmel, Karl Heinz Weiss |
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| 520 | |a Current guidelines favor the use of chelating agents (d-penicillamine, trientine) in first line therapy of symptomatic Wilson disease patients. Development of chelator induced immunological adverse events are a concern especially under d-penicillamine therapy. This study assessed the prevalence of co-existing or therapy-related immune-mediated diseases in Wilson disease patients, and evaluated the role of antinuclear antibodies in therapy monitoring. | ||
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