Buchumschlag

Meta-analysis of reconstruction techniques after low anterior resection for rectal cancer

Background Options for reconstruction after low anterior resection (LAR) for rectal cancer include straight or side-to-end coloanal anastomosis (CAA), colonic J pouch and transverse coloplasty. This systematic review compared these techniques in terms of function, surgical outcomes and quality of li...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hüttner, Felix (VerfasserIn) , Tenckhoff, Solveig (VerfasserIn) , Jensen, Katrin (VerfasserIn) , Uhlmann, Lorenz (VerfasserIn) , Kulu, Yakup (VerfasserIn) , Büchler, Markus W. (VerfasserIn) , Diener, Markus K. (VerfasserIn) , Ulrich, Alexis (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 31 March 2015
In: The British journal of surgery
Year: 2015, Jahrgang: 102, Heft: 7, Pages: 735-745
ISSN:1365-2168
DOI:10.1002/bjs.9782
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/bjs.9782
Verlag, lizenzpflichtig, Volltext: https://bjssjournals.onlinelibrary.wiley.com/doi/abs/10.1002/bjs.9782
Volltext
Verfasserangaben:F.J. Hüttner, S. Tenckhoff, K. Jensen, L. Uhlmann, Y. Kulu, M.W. Büchler, M.K. Diener and A. Ulrich
Beschreibung
Zusammenfassung:Background Options for reconstruction after low anterior resection (LAR) for rectal cancer include straight or side-to-end coloanal anastomosis (CAA), colonic J pouch and transverse coloplasty. This systematic review compared these techniques in terms of function, surgical outcomes and quality of life. Methods A systematic literature search (MEDLINE, Embase and the Cochrane Library, from inception of the databases until November 2014) was conducted to identify randomized clinical trials comparing reconstructive techniques after LAR. Random-effects meta-analyses were carried out, and results presented as weighted odds ratios or mean differences with corresponding 95 per cent c.i. A network meta-analysis was conducted for the outcome anastomotic leakage. Results The search yielded 965 results; 21 trials comprising data from 1636 patients were included. Colonic J pouch was associated with lower stool frequency and antidiarrhoeal medication use for up to 1 year after surgery compared with straight CAA. Transverse coloplasty and side-to-end CAA had similar functional outcomes to the colonic J pouch. No superiority was found for any of the techniques in terms of anastomotic leak rate. Conclusion Colonic J pouch and side-to-end CAA or transverse coloplasty lead to a better functional outcome than straight CAA for the first year after surgery.
Beschreibung:Gesehen am 03.06.2020
Beschreibung:Online Resource
ISSN:1365-2168
DOI:10.1002/bjs.9782

Ähnliche Einträge