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Significant prevalence of sickle cell disease in Southwest Germany: results from a birth cohort study indicate the necessity for newborn screening

Children with sickle cell disease (SCD) benefit from newborn screening, because life-threatening complications can be prevented by pre-symptomatic diagnosis. In Germany, the immigration of people from endemic countries is steadily growing. Comprehensive data about the epidemiology and prevalence of...

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Main Authors: Kunz, Joachim (Author) , Awad, Saida Beatrix (Author) , Happich, Margit (Author) , Muckenthaler, Lena (Author) , Lindner, Martin (Author) , Gramer, Gwendolyn (Author) , Okun, Jürgen G. (Author) , Hoffmann, Georg F. (Author) , Bruckner, Thomas (Author) , Muckenthaler, Martina (Author) , Kulozik, Andreas (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: Annals of hematology
Year: 2015, Volume: 95, Issue: 3, Pages: 397-402
ISSN:1432-0584
DOI:10.1007/s00277-015-2573-y
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00277-015-2573-y
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs00277-015-2573-y
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Author Notes:Joachim B. Kunz, Saida Awad, Margit Happich, Lena Muckenthaler, Martin Lindner, Gwendolyn Gramer, Jürgen G. Okun, Georg F. Hoffmann, Thomas Bruckner, Martina U. Muckenthaler, Andreas E. Kulozik
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Summary:Children with sickle cell disease (SCD) benefit from newborn screening, because life-threatening complications can be prevented by pre-symptomatic diagnosis. In Germany, the immigration of people from endemic countries is steadily growing. Comprehensive data about the epidemiology and prevalence of SCD in Germany are however lacking, and SCD is not included in the national newborn screening program. We provide data on the prevalence of SCD in a population from both urban and rural areas in Southwest Germany.
Item Description:Published online: 12 December 2015
Gesehen am 03.06.2020
Physical Description:Online Resource
ISSN:1432-0584
DOI:10.1007/s00277-015-2573-y

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