Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease
Key Points. Heme and iron induce macrophage phenotypic switching toward an M1 proinflammatory phenotype.By scavenging free heme, hemopexin reverts heme-induced
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
[28 January 2016]
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| In: |
Blood
Year: 2016, Jahrgang: 127, Heft: 4, Pages: 473-486 |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood-2015-08-663245 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood-2015-08-663245 Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/127/4/473/35037/Hemopexin-therapy-reverts-heme-induced 
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| Verfasserangaben: | Francesca Vinchi, Milene Costa da Silva, Giada Ingoglia, Sara Petrillo, Nathan Brinkman, Adrian Zuercher, Adelheid Cerwenka, Emanuela Tolosano, Martina U. Muckenthaler |
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